http://purl.uniprot.org/citations/36332016 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/36332016 | http://www.w3.org/2000/01/rdf-schema#comment | "Two fundamental elements of pre-implantation embryogenesis are cells' intrinsic self-organization program and their developmental plasticity, which allows embryos to compensate for alterations in cell position and number; yet, these elements are still poorly understood. To be able to decipher these features, we established culture conditions that enable the two fates of blastocysts' extraembryonic lineages-the primitive endoderm and the trophectoderm-to coexist. This plasticity emerges following the mechanisms of the first lineage segregation in the mouse embryo, and it manifests as an extended potential for extraembryonic chimerism during the pre-implantation embryogenesis. Moreover, this shared state enables robust assembly into higher-order blastocyst-like structures, thus combining both the cell fate plasticity and self-organization features of the early extraembryonic lineages."xsd:string |
http://purl.uniprot.org/citations/36332016 | http://purl.org/dc/terms/identifier | "doi:10.1126/sciadv.abl9583"xsd:string |
http://purl.uniprot.org/citations/36332016 | http://purl.uniprot.org/core/author | "Brinkmann H."xsd:string |
http://purl.uniprot.org/citations/36332016 | http://purl.uniprot.org/core/author | "Chen R."xsd:string |
http://purl.uniprot.org/citations/36332016 | http://purl.uniprot.org/core/author | "Kim Y.S."xsd:string |
http://purl.uniprot.org/citations/36332016 | http://purl.uniprot.org/core/author | "Fan R."xsd:string |
http://purl.uniprot.org/citations/36332016 | http://purl.uniprot.org/core/author | "Kim K.P."xsd:string |
http://purl.uniprot.org/citations/36332016 | http://purl.uniprot.org/core/author | "Stehling M."xsd:string |
http://purl.uniprot.org/citations/36332016 | http://purl.uniprot.org/core/author | "Jeong H.W."xsd:string |
http://purl.uniprot.org/citations/36332016 | http://purl.uniprot.org/core/author | "Adams R.H."xsd:string |
http://purl.uniprot.org/citations/36332016 | http://purl.uniprot.org/core/author | "Vaquerizas J.M."xsd:string |
http://purl.uniprot.org/citations/36332016 | http://purl.uniprot.org/core/author | "Scholer H.R."xsd:string |
http://purl.uniprot.org/citations/36332016 | http://purl.uniprot.org/core/author | "Bedzhov I."xsd:string |
http://purl.uniprot.org/citations/36332016 | http://purl.uniprot.org/core/author | "Ing-Simmons E."xsd:string |
http://purl.uniprot.org/citations/36332016 | http://purl.uniprot.org/core/author | "Sathyanarayanan A."xsd:string |
http://purl.uniprot.org/citations/36332016 | http://purl.uniprot.org/core/author | "Ozguldez H.O."xsd:string |
http://purl.uniprot.org/citations/36332016 | http://purl.uniprot.org/core/author | "Duethorn B."xsd:string |
http://purl.uniprot.org/citations/36332016 | http://purl.uniprot.org/core/date | "2022"xsd:gYear |
http://purl.uniprot.org/citations/36332016 | http://purl.uniprot.org/core/name | "Sci Adv"xsd:string |
http://purl.uniprot.org/citations/36332016 | http://purl.uniprot.org/core/pages | "eabl9583"xsd:string |
http://purl.uniprot.org/citations/36332016 | http://purl.uniprot.org/core/title | "Early developmental plasticity enables the induction of an intermediate extraembryonic cell state."xsd:string |
http://purl.uniprot.org/citations/36332016 | http://purl.uniprot.org/core/volume | "8"xsd:string |
http://purl.uniprot.org/citations/36332016 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/36332016 |
http://purl.uniprot.org/citations/36332016 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/36332016 |