http://purl.uniprot.org/citations/36344519 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/36344519 | http://www.w3.org/2000/01/rdf-schema#comment | "A major hurdle for single particle cryo-EM in structural determination lies in the specimen preparation impaired by the air-water interface (AWI) and preferential particle-orientation problems. In this work, we develop functionalized graphene grids with various charges via a dediazoniation reaction for cryo-EM specimen preparation. The graphene grids are paraffin-assistant fabricated, which appear with less contaminations compared with those produced by polymer transfer method. By applying onto three different types of macromolecules, we demonstrate that the high-yield charged graphene grids bring macromolecules away from the AWI and enable adjustable particle-orientation distribution for more robust single particle cryo-EM structural determination."xsd:string |
http://purl.uniprot.org/citations/36344519 | http://purl.org/dc/terms/identifier | "doi:10.1038/s41467-022-34579-w"xsd:string |
http://purl.uniprot.org/citations/36344519 | http://purl.uniprot.org/core/author | "Liu Y."xsd:string |
http://purl.uniprot.org/citations/36344519 | http://purl.uniprot.org/core/author | "Lu Y."xsd:string |
http://purl.uniprot.org/citations/36344519 | http://purl.uniprot.org/core/author | "Liu N."xsd:string |
http://purl.uniprot.org/citations/36344519 | http://purl.uniprot.org/core/author | "Jia X."xsd:string |
http://purl.uniprot.org/citations/36344519 | http://purl.uniprot.org/core/author | "Yang J."xsd:string |
http://purl.uniprot.org/citations/36344519 | http://purl.uniprot.org/core/author | "Wang J."xsd:string |
http://purl.uniprot.org/citations/36344519 | http://purl.uniprot.org/core/author | "Wang H.W."xsd:string |
http://purl.uniprot.org/citations/36344519 | http://purl.uniprot.org/core/author | "Zheng L."xsd:string |
http://purl.uniprot.org/citations/36344519 | http://purl.uniprot.org/core/author | "Peng H."xsd:string |
http://purl.uniprot.org/citations/36344519 | http://purl.uniprot.org/core/author | "Rao Y."xsd:string |
http://purl.uniprot.org/citations/36344519 | http://purl.uniprot.org/core/author | "Zi Q."xsd:string |
http://purl.uniprot.org/citations/36344519 | http://purl.uniprot.org/core/date | "2022"xsd:gYear |
http://purl.uniprot.org/citations/36344519 | http://purl.uniprot.org/core/name | "Nat Commun"xsd:string |
http://purl.uniprot.org/citations/36344519 | http://purl.uniprot.org/core/pages | "6718"xsd:string |
http://purl.uniprot.org/citations/36344519 | http://purl.uniprot.org/core/title | "Functionalized graphene grids with various charges for single-particle cryo-EM."xsd:string |
http://purl.uniprot.org/citations/36344519 | http://purl.uniprot.org/core/volume | "13"xsd:string |
http://purl.uniprot.org/citations/36344519 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/36344519 |
http://purl.uniprot.org/citations/36344519 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/36344519 |
http://purl.uniprot.org/uniprot/#_P0A3U0-mappedCitation-36344519 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/36344519 |
http://purl.uniprot.org/uniprot/P0A3U0 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/36344519 |