| http://purl.uniprot.org/citations/36395073 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/36395073 | http://www.w3.org/2000/01/rdf-schema#comment | "In briefThe testis-specific transcription factor, TCFL5, expressed in pachytene spermatocytes regulates the meiotic gene expression program in collaboration with the transcription factor A-MYB.AbstractIn male mice, the transcription factors STRA8 and MEISON initiate meiosis I. We report that STRA8/MEISON activates the transcription factors A-MYB and TCFL5, which together reprogram gene expression after spermatogonia enter into meiosis. TCFL5 promotes the transcription of genes required for meiosis, mRNA turnover, miR-34/449 production, meiotic exit, and spermiogenesis. This transcriptional architecture is conserved in rhesus macaque, suggesting TCFL5 plays a central role in meiosis and spermiogenesis in placental mammals. Tcfl5em1/em1 mutants are sterile, and spermatogenesis arrests at the mid- or late-pachytene stage of meiosis. Moreover, Tcfl5+/em1 mutants produce fewer motile sperm."xsd:string |
| http://purl.uniprot.org/citations/36395073 | http://purl.org/dc/terms/identifier | "doi:10.1530/rep-22-0355"xsd:string |
| http://purl.uniprot.org/citations/36395073 | http://purl.uniprot.org/core/author | "Yu T."xsd:string |
| http://purl.uniprot.org/citations/36395073 | http://purl.uniprot.org/core/author | "Gainetdinov I."xsd:string |
| http://purl.uniprot.org/citations/36395073 | http://purl.uniprot.org/core/author | "Zamore P.D."xsd:string |
| http://purl.uniprot.org/citations/36395073 | http://purl.uniprot.org/core/author | "Weng Z."xsd:string |
| http://purl.uniprot.org/citations/36395073 | http://purl.uniprot.org/core/author | "Mou H."xsd:string |
| http://purl.uniprot.org/citations/36395073 | http://purl.uniprot.org/core/author | "Arif A."xsd:string |
| http://purl.uniprot.org/citations/36395073 | http://purl.uniprot.org/core/author | "de Rooij D.G."xsd:string |
| http://purl.uniprot.org/citations/36395073 | http://purl.uniprot.org/core/author | "Colpan C."xsd:string |
| http://purl.uniprot.org/citations/36395073 | http://purl.uniprot.org/core/author | "Eghbali A."xsd:string |
| http://purl.uniprot.org/citations/36395073 | http://purl.uniprot.org/core/author | "Ozata D.M."xsd:string |
| http://purl.uniprot.org/citations/36395073 | http://purl.uniprot.org/core/author | "Biasini A."xsd:string |
| http://purl.uniprot.org/citations/36395073 | http://purl.uniprot.org/core/author | "Cecchini K."xsd:string |
| http://purl.uniprot.org/citations/36395073 | http://purl.uniprot.org/core/author | "Saflund M."xsd:string |
| http://purl.uniprot.org/citations/36395073 | http://purl.uniprot.org/core/date | "2023"xsd:gYear |
| http://purl.uniprot.org/citations/36395073 | http://purl.uniprot.org/core/name | "Reproduction"xsd:string |
| http://purl.uniprot.org/citations/36395073 | http://purl.uniprot.org/core/pages | "183-196"xsd:string |
| http://purl.uniprot.org/citations/36395073 | http://purl.uniprot.org/core/title | "The transcription factor TCFL5 responds to A-MYB to elaborate the male meiotic program in mice."xsd:string |
| http://purl.uniprot.org/citations/36395073 | http://purl.uniprot.org/core/volume | "165"xsd:string |
| http://purl.uniprot.org/citations/36395073 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/36395073 |
| http://purl.uniprot.org/citations/36395073 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/36395073 |
| http://purl.uniprot.org/uniprot/#_Q32NY8-mappedCitation-36395073 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/36395073 |
| http://purl.uniprot.org/uniprot/#_Q3V133-mappedCitation-36395073 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/36395073 |