| http://purl.uniprot.org/citations/36461782 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/36461782 | http://www.w3.org/2000/01/rdf-schema#comment | "Dynein is a microtubule-dependent motor protein required for cell division, retrograde intracellular transport, and intraflagellar transport (IFT). Dynein 1 and dynein 2 serve as molecular motors in the cytoplasm and cilia, respectively. Each dynein consists of multiple subunits. Although the components of dynein 1 and dynein 2 are different and specific in most species, a previous study has suggested that dynein intermediate chain subunit DYCI-1 is shared by both dynein 1 and 2 in Caenorhabditis elegans (C. elegans). Here, we show that C. elegans has two dynein intermediate chains-DYCI-1 and WDR-60-and their functions are different. Mutational analysis showed that dyci-1 is essential for the retrograde axonal transport of synaptic vesicles. In the same mutant allele, IFT is not affected at all. Instead, wdr-60 is essential for IFT. Thus, we suggest that dynein 1 and dynein 2 have specific intermediate chains in C. elegans as in other organisms."xsd:string |
| http://purl.uniprot.org/citations/36461782 | http://purl.org/dc/terms/identifier | "doi:10.1111/gtc.12996"xsd:string |
| http://purl.uniprot.org/citations/36461782 | http://purl.uniprot.org/core/author | "Niwa S."xsd:string |
| http://purl.uniprot.org/citations/36461782 | http://purl.uniprot.org/core/author | "Higashida M."xsd:string |
| http://purl.uniprot.org/citations/36461782 | http://purl.uniprot.org/core/date | "2023"xsd:gYear |
| http://purl.uniprot.org/citations/36461782 | http://purl.uniprot.org/core/name | "Genes Cells"xsd:string |
| http://purl.uniprot.org/citations/36461782 | http://purl.uniprot.org/core/pages | "97-110"xsd:string |
| http://purl.uniprot.org/citations/36461782 | http://purl.uniprot.org/core/title | "Dynein intermediate chains DYCI-1 and WDR-60 have specific functions in Caenorhabditis elegans."xsd:string |
| http://purl.uniprot.org/citations/36461782 | http://purl.uniprot.org/core/volume | "28"xsd:string |
| http://purl.uniprot.org/citations/36461782 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/36461782 |
| http://purl.uniprot.org/citations/36461782 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/36461782 |
| http://purl.uniprot.org/uniprot/#_A0A486WV95-mappedCitation-36461782 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/36461782 |
| http://purl.uniprot.org/uniprot/#_O45087-mappedCitation-36461782 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/36461782 |
| http://purl.uniprot.org/uniprot/#_Q18263-mappedCitation-36461782 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/36461782 |
| http://purl.uniprot.org/uniprot/A0A486WV95 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/36461782 |
| http://purl.uniprot.org/uniprot/Q18263 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/36461782 |
| http://purl.uniprot.org/uniprot/O45087 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/36461782 |