http://purl.uniprot.org/citations/36811145 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/36811145 | http://www.w3.org/2000/01/rdf-schema#comment | "The maintenance of sodium/potassium (Na+ /K+ ) homeostasis in plant cells is essential for salt tolerance. Plants export excess Na+ out of cells mainly through the Salt Overly Sensitive (SOS) pathway, activated by a calcium signal; however, it is unknown whether other signals regulate the SOS pathway and how K+ uptake is regulated under salt stress. Phosphatidic acid (PA) is emerging as a lipid signaling molecule that modulates cellular processes in development and the response to stimuli. Here, we show that PA binds to the residue Lys57 in SOS2, a core member of the SOS pathway, under salt stress, promoting the activity and plasma membrane localization of SOS2, which activates the Na+ /H+ antiporter SOS1 to promote the Na+ efflux. In addition, we reveal that PA promotes the phosphorylation of SOS3-like calcium-binding protein 8 (SCaBP8) by SOS2 under salt stress, which attenuates the SCaBP8-mediated inhibition of Arabidopsis K+ transporter 1 (AKT1), an inward-rectifying K+ channel. These findings suggest that PA regulates the SOS pathway and AKT1 activity under salt stress, promoting Na+ efflux and K+ influx to maintain Na+ /K+ homeostasis."xsd:string |
http://purl.uniprot.org/citations/36811145 | http://purl.org/dc/terms/identifier | "doi:10.15252/embj.2022112401"xsd:string |
http://purl.uniprot.org/citations/36811145 | http://purl.uniprot.org/core/author | "Guo Y."xsd:string |
http://purl.uniprot.org/citations/36811145 | http://purl.uniprot.org/core/author | "Jin W."xsd:string |
http://purl.uniprot.org/citations/36811145 | http://purl.uniprot.org/core/author | "Han X."xsd:string |
http://purl.uniprot.org/citations/36811145 | http://purl.uniprot.org/core/author | "Li J."xsd:string |
http://purl.uniprot.org/citations/36811145 | http://purl.uniprot.org/core/author | "Li Y."xsd:string |
http://purl.uniprot.org/citations/36811145 | http://purl.uniprot.org/core/author | "Shen L."xsd:string |
http://purl.uniprot.org/citations/36811145 | http://purl.uniprot.org/core/author | "Wang Y."xsd:string |
http://purl.uniprot.org/citations/36811145 | http://purl.uniprot.org/core/author | "Zhang W."xsd:string |
http://purl.uniprot.org/citations/36811145 | http://purl.uniprot.org/core/author | "Zhang Z."xsd:string |
http://purl.uniprot.org/citations/36811145 | http://purl.uniprot.org/core/author | "Yang S."xsd:string |
http://purl.uniprot.org/citations/36811145 | http://purl.uniprot.org/core/author | "Yang Y."xsd:string |
http://purl.uniprot.org/citations/36811145 | http://purl.uniprot.org/core/author | "Fan W."xsd:string |
http://purl.uniprot.org/citations/36811145 | http://purl.uniprot.org/core/author | "He G."xsd:string |
http://purl.uniprot.org/citations/36811145 | http://purl.uniprot.org/core/date | "2023"xsd:gYear |
http://purl.uniprot.org/citations/36811145 | http://purl.uniprot.org/core/name | "EMBO J"xsd:string |
http://purl.uniprot.org/citations/36811145 | http://purl.uniprot.org/core/pages | "e112401"xsd:string |
http://purl.uniprot.org/citations/36811145 | http://purl.uniprot.org/core/title | "Phosphatidic acid-regulated SOS2 controls sodium and potassium homeostasis in Arabidopsis under salt stress."xsd:string |
http://purl.uniprot.org/citations/36811145 | http://purl.uniprot.org/core/volume | "42"xsd:string |
http://purl.uniprot.org/citations/36811145 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/36811145 |
http://purl.uniprot.org/citations/36811145 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/36811145 |
http://purl.uniprot.org/uniprot/#_A0A384KKJ4-mappedCitation-36811145 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/36811145 |
http://purl.uniprot.org/uniprot/#_A0A1P8BGJ7-mappedCitation-36811145 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/36811145 |