http://purl.uniprot.org/citations/3692484 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/3692484 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/3692484 | http://www.w3.org/2000/01/rdf-schema#comment | "Various cDNAs for creatine kinase type B (CK-B) were isolated from human cDNA libraries using a 26-oligonucleotide guess-mer probe. One of the cDNAs appeared to be almost full-length and contained an open reading frame coding for the 381 amino acid residues of the human CK-B polypeptide. The nucleotide sequences of the translated region as well as the primary protein structure show a high degree of homology with known CK-B and CK-M sequences of other vertebrates. The level of CK-B RNA as a measure of CK-B gene activity was determined in various human tissues and cultured cells. Our results confirm that CK-B is expressed in a tissue-specific manner and give support to the previously proposed relation between CK-B gene activity and cell proliferation. Screening of genomic DNA with various cDNA regions as probes revealed that there is only one CK-B gene per haploid genome. Gene cloning and sequencing indicated that CK-B is coded for by a relatively small gene of 3.2 kb in size, which is partially overlapped by an HTF island (A. P. Bird (1986) Nature (London) 321, 557-558) with an extremely high G + C content at its 5' end."xsd:string |
http://purl.uniprot.org/citations/3692484 | http://purl.org/dc/terms/identifier | "doi:10.1016/0888-7543(87)90004-8"xsd:string |
http://purl.uniprot.org/citations/3692484 | http://purl.org/dc/terms/identifier | "doi:10.1016/0888-7543(87)90004-8"xsd:string |
http://purl.uniprot.org/citations/3692484 | http://purl.uniprot.org/core/author | "Wieringa B."xsd:string |
http://purl.uniprot.org/citations/3692484 | http://purl.uniprot.org/core/author | "Wieringa B."xsd:string |
http://purl.uniprot.org/citations/3692484 | http://purl.uniprot.org/core/author | "Mariman E.C.M."xsd:string |
http://purl.uniprot.org/citations/3692484 | http://purl.uniprot.org/core/author | "Mariman E.C.M."xsd:string |
http://purl.uniprot.org/citations/3692484 | http://purl.uniprot.org/core/author | "Broers C.A.M."xsd:string |
http://purl.uniprot.org/citations/3692484 | http://purl.uniprot.org/core/author | "Broers C.A.M."xsd:string |
http://purl.uniprot.org/citations/3692484 | http://purl.uniprot.org/core/author | "Claesen C.A.A."xsd:string |
http://purl.uniprot.org/citations/3692484 | http://purl.uniprot.org/core/author | "Claesen C.A.A."xsd:string |
http://purl.uniprot.org/citations/3692484 | http://purl.uniprot.org/core/author | "Tesser G.I."xsd:string |
http://purl.uniprot.org/citations/3692484 | http://purl.uniprot.org/core/author | "Tesser G.I."xsd:string |
http://purl.uniprot.org/citations/3692484 | http://purl.uniprot.org/core/date | "1987"xsd:gYear |
http://purl.uniprot.org/citations/3692484 | http://purl.uniprot.org/core/date | "1987"xsd:gYear |
http://purl.uniprot.org/citations/3692484 | http://purl.uniprot.org/core/name | "Genomics"xsd:string |
http://purl.uniprot.org/citations/3692484 | http://purl.uniprot.org/core/name | "Genomics"xsd:string |
http://purl.uniprot.org/citations/3692484 | http://purl.uniprot.org/core/pages | "126-137"xsd:string |
http://purl.uniprot.org/citations/3692484 | http://purl.uniprot.org/core/pages | "126-137"xsd:string |
http://purl.uniprot.org/citations/3692484 | http://purl.uniprot.org/core/title | "Structure and expression of the human creatine kinase B gene."xsd:string |
http://purl.uniprot.org/citations/3692484 | http://purl.uniprot.org/core/title | "Structure and expression of the human creatine kinase B gene."xsd:string |
http://purl.uniprot.org/citations/3692484 | http://purl.uniprot.org/core/volume | "1"xsd:string |
http://purl.uniprot.org/citations/3692484 | http://purl.uniprot.org/core/volume | "1"xsd:string |