| http://purl.uniprot.org/citations/36952351 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/36952351 | http://www.w3.org/2000/01/rdf-schema#comment | "The orchestrated activity of the mitochondrial respiratory or electron transport chain (ETC) and ATP synthase convert reduction power (NADH, FADH2) into ATP, the cell's energy currency in a process named oxidative phosphorylation (OXPHOS). Three out of the four ETC complexes are found in supramolecular assemblies: complex I, III, and IV form the respiratory supercomplexes (SC). The plasticity model suggests that SC formation is a form of adaptation to changing conditions such as energy supply, redox state, and stress. Complex I, the NADH-dehydrogenase, is part of the largest supercomplex (CI + CIII2 + CIVn). Here, we demonstrate the role of NDUFB10, a subunit of the membrane arm of complex I, in complex I and supercomplex assembly on the one hand and bioenergetics function on the other. NDUFB10 knockout was correlated with a decrease of SCAF1, a supercomplex assembly factor, and a reduction of respiration and mitochondrial membrane potential. This likely is due to loss of proton pumping since the CI P P -module is downregulated and the P D -module is completely abolished in NDUFB10 knock outs."xsd:string |
| http://purl.uniprot.org/citations/36952351 | http://purl.org/dc/terms/identifier | "doi:10.1515/hsz-2022-0309"xsd:string |
| http://purl.uniprot.org/citations/36952351 | http://purl.uniprot.org/core/author | "Hippler M."xsd:string |
| http://purl.uniprot.org/citations/36952351 | http://purl.uniprot.org/core/author | "Scholz M."xsd:string |
| http://purl.uniprot.org/citations/36952351 | http://purl.uniprot.org/core/author | "Enriquez J.A."xsd:string |
| http://purl.uniprot.org/citations/36952351 | http://purl.uniprot.org/core/author | "Psathaki O.E."xsd:string |
| http://purl.uniprot.org/citations/36952351 | http://purl.uniprot.org/core/author | "Busch K.B."xsd:string |
| http://purl.uniprot.org/citations/36952351 | http://purl.uniprot.org/core/author | "Marx N."xsd:string |
| http://purl.uniprot.org/citations/36952351 | http://purl.uniprot.org/core/author | "Arroum T."xsd:string |
| http://purl.uniprot.org/citations/36952351 | http://purl.uniprot.org/core/author | "Borowski M.T."xsd:string |
| http://purl.uniprot.org/citations/36952351 | http://purl.uniprot.org/core/author | "Schmelter F."xsd:string |
| http://purl.uniprot.org/citations/36952351 | http://purl.uniprot.org/core/date | "2023"xsd:gYear |
| http://purl.uniprot.org/citations/36952351 | http://purl.uniprot.org/core/name | "Biol Chem"xsd:string |
| http://purl.uniprot.org/citations/36952351 | http://purl.uniprot.org/core/pages | "399-415"xsd:string |
| http://purl.uniprot.org/citations/36952351 | http://purl.uniprot.org/core/title | "Loss of respiratory complex I subunit NDUFB10 affects complex I assembly and supercomplex formation."xsd:string |
| http://purl.uniprot.org/citations/36952351 | http://purl.uniprot.org/core/volume | "404"xsd:string |
| http://purl.uniprot.org/citations/36952351 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/36952351 |
| http://purl.uniprot.org/citations/36952351 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/36952351 |
| http://purl.uniprot.org/uniprot/#_A8K761-mappedCitation-36952351 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/36952351 |
| http://purl.uniprot.org/uniprot/#_O96000-mappedCitation-36952351 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/36952351 |
| http://purl.uniprot.org/uniprot/#_Q96RX5-mappedCitation-36952351 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/36952351 |
| http://purl.uniprot.org/uniprot/A8K761 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/36952351 |
| http://purl.uniprot.org/uniprot/O96000 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/36952351 |
| http://purl.uniprot.org/uniprot/Q96RX5 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/36952351 |