| http://purl.uniprot.org/citations/37073589 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/37073589 | http://www.w3.org/2000/01/rdf-schema#comment | "Biological and genetic factors, as well as contextual influences, contribute to the etiology of externalizing behaviors in children and adolescents. The current project used a longitudinal design to examine how individual vulnerability for externalizing behavior is influenced by the interplay among biological/genetic and environmental factors, and how this occurs across development. We investigated the influence of dopamine receptor D4 genotype (DRD4), child temperament, and household chaos on children's externalizing behaviors using a sample of twins/triplets tested at the ages of 4 and 5 years (n = 229), including a subset of these who were tested again in middle childhood (ages 7-13 years; n = 174). Multilevel linear regression modeling demonstrated that the DRD4-7repeat genotype, 4-year-old negative affectivity, and household chaos at the age of 4 years were related to 5-year-old externalizing behaviors. Stability in externalizing behaviors from the age of 5 years to middle childhood was demonstrated. A significant interaction between DRD4 and household chaos showed that children with no 7-repeat DRD4 alleles had significantly higher levels of externalizing in homes with extremely low levels of parent-reported chaos, suggesting a "goodness-of-fit" pattern of gene-environment interaction. These findings suggest that risk for childhood externalizing behaviors is likely multifaceted and differs across developmental periods."xsd:string |
| http://purl.uniprot.org/citations/37073589 | http://purl.org/dc/terms/identifier | "doi:10.1002/dev.22387"xsd:string |
| http://purl.uniprot.org/citations/37073589 | http://purl.uniprot.org/core/author | "DiLalla L.F."xsd:string |
| http://purl.uniprot.org/citations/37073589 | http://purl.uniprot.org/core/author | "Jamnik M.R."xsd:string |
| http://purl.uniprot.org/citations/37073589 | http://purl.uniprot.org/core/date | "2023"xsd:gYear |
| http://purl.uniprot.org/citations/37073589 | http://purl.uniprot.org/core/name | "Dev Psychobiol"xsd:string |
| http://purl.uniprot.org/citations/37073589 | http://purl.uniprot.org/core/pages | "e22387"xsd:string |
| http://purl.uniprot.org/citations/37073589 | http://purl.uniprot.org/core/title | "The impact of dopamine receptor D4, temperamental negativity, and household chaos on young twins' externalizing behaviors."xsd:string |
| http://purl.uniprot.org/citations/37073589 | http://purl.uniprot.org/core/volume | "65"xsd:string |
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