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http://purl.uniprot.org/citations/37148880http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/37148880http://www.w3.org/2000/01/rdf-schema#comment"Defining the mechanisms that govern heart development is essential for identifying the etiology of congenital heart disease. Here, quantitative proteomics was used to measure temporal changes in the proteome at critical stages of murine embryonic heart development. Global temporal profiles of the over 7,300 proteins uncovered signature cardiac protein interaction networks that linked protein dynamics with molecular pathways. Using this integrated dataset, we identified and demonstrated a functional role for the mevalonate pathway in regulating the cell cycle of embryonic cardiomyocytes. Overall, our proteomic datasets are a resource for studying events that regulate embryonic heart development and contribute to congenital heart disease."xsd:string
http://purl.uniprot.org/citations/37148880http://purl.org/dc/terms/identifier"doi:10.1016/j.devcel.2023.04.011"xsd:string
http://purl.uniprot.org/citations/37148880http://purl.uniprot.org/core/author"Cristea I.M."xsd:string
http://purl.uniprot.org/citations/37148880http://purl.uniprot.org/core/author"Greco T.M."xsd:string
http://purl.uniprot.org/citations/37148880http://purl.uniprot.org/core/author"Cohen S."xsd:string
http://purl.uniprot.org/citations/37148880http://purl.uniprot.org/core/author"Miner G.E."xsd:string
http://purl.uniprot.org/citations/37148880http://purl.uniprot.org/core/author"Conlon F.L."xsd:string
http://purl.uniprot.org/citations/37148880http://purl.uniprot.org/core/author"Edwards W."xsd:string
http://purl.uniprot.org/citations/37148880http://purl.uniprot.org/core/author"Herring L."xsd:string
http://purl.uniprot.org/citations/37148880http://purl.uniprot.org/core/author"Barker N.K."xsd:string
http://purl.uniprot.org/citations/37148880http://purl.uniprot.org/core/date"2023"xsd:gYear
http://purl.uniprot.org/citations/37148880http://purl.uniprot.org/core/name"Dev Cell"xsd:string
http://purl.uniprot.org/citations/37148880http://purl.uniprot.org/core/pages"1087-1105.e4"xsd:string
http://purl.uniprot.org/citations/37148880http://purl.uniprot.org/core/title"Quantitative proteomic profiling identifies global protein network dynamics in murine embryonic heart development."xsd:string
http://purl.uniprot.org/citations/37148880http://purl.uniprot.org/core/volume"58"xsd:string
http://purl.uniprot.org/citations/37148880http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/37148880
http://purl.uniprot.org/citations/37148880http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/37148880
http://purl.uniprot.org/uniprot/#_E9Q149-mappedCitation-37148880http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/37148880
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http://purl.uniprot.org/uniprot/#_A0A1Y7VJZ1-mappedCitation-37148880http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/37148880
http://purl.uniprot.org/uniprot/#_A0A1Y7VLK7-mappedCitation-37148880http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/37148880
http://purl.uniprot.org/uniprot/#_A0A1Y7VLQ5-mappedCitation-37148880http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/37148880
http://purl.uniprot.org/uniprot/#_A0A1Y7VM16-mappedCitation-37148880http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/37148880
http://purl.uniprot.org/uniprot/#_A0A1Y7VMJ4-mappedCitation-37148880http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/37148880