http://purl.uniprot.org/citations/37267956 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/37267956 | http://www.w3.org/2000/01/rdf-schema#comment | "One of cannabis' most iconic effects is the stimulation of hedonic high-calorie eating-the "munchies"-yet habitual cannabis users are, on average, leaner than non-users. We asked whether this phenotype might result from lasting changes in energy balance established during adolescence, when use of the drug often begins. We found that daily low-dose administration of cannabis' intoxicating constituent, Δ9-tetrahydrocannabinol (THC), to adolescent male mice causes an adult metabolic phenotype characterized by reduced fat mass, increased lean mass and utilization of fat as fuel, partial resistance to diet-induced obesity and dyslipidemia, enhanced thermogenesis, and impaired cold- and β-adrenergic receptor-stimulated lipolysis. Further analyses revealed that this phenotype is associated with molecular anomalies in the adipose organ, including ectopic overexpression of muscle-associated proteins and heightened anabolic processing. Thus, adolescent exposure to THC may promote an enduring "pseudo-lean" state that superficially resembles healthy leanness but might in fact be rooted in adipose organ dysfunction."xsd:string |
http://purl.uniprot.org/citations/37267956 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.cmet.2023.05.002"xsd:string |
http://purl.uniprot.org/citations/37267956 | http://purl.uniprot.org/core/author | "Huang L."xsd:string |
http://purl.uniprot.org/citations/37267956 | http://purl.uniprot.org/core/author | "Lin L."xsd:string |
http://purl.uniprot.org/citations/37267956 | http://purl.uniprot.org/core/author | "Le J."xsd:string |
http://purl.uniprot.org/citations/37267956 | http://purl.uniprot.org/core/author | "Tang L."xsd:string |
http://purl.uniprot.org/citations/37267956 | http://purl.uniprot.org/core/author | "Yang Q."xsd:string |
http://purl.uniprot.org/citations/37267956 | http://purl.uniprot.org/core/author | "Yu C."xsd:string |
http://purl.uniprot.org/citations/37267956 | http://purl.uniprot.org/core/author | "Ramirez J."xsd:string |
http://purl.uniprot.org/citations/37267956 | http://purl.uniprot.org/core/author | "Lee H.L."xsd:string |
http://purl.uniprot.org/citations/37267956 | http://purl.uniprot.org/core/author | "Wood C."xsd:string |
http://purl.uniprot.org/citations/37267956 | http://purl.uniprot.org/core/author | "Su S."xsd:string |
http://purl.uniprot.org/citations/37267956 | http://purl.uniprot.org/core/author | "Cinti S."xsd:string |
http://purl.uniprot.org/citations/37267956 | http://purl.uniprot.org/core/author | "Piomelli D."xsd:string |
http://purl.uniprot.org/citations/37267956 | http://purl.uniprot.org/core/author | "Jung K.M."xsd:string |
http://purl.uniprot.org/citations/37267956 | http://purl.uniprot.org/core/author | "Jang C."xsd:string |
http://purl.uniprot.org/citations/37267956 | http://purl.uniprot.org/core/author | "Palese F."xsd:string |
http://purl.uniprot.org/citations/37267956 | http://purl.uniprot.org/core/author | "Colleluori G."xsd:string |
http://purl.uniprot.org/citations/37267956 | http://purl.uniprot.org/core/author | "Fotio Y."xsd:string |
http://purl.uniprot.org/citations/37267956 | http://purl.uniprot.org/core/author | "Torrens A."xsd:string |
http://purl.uniprot.org/citations/37267956 | http://purl.uniprot.org/core/author | "DiPatrizio N."xsd:string |
http://purl.uniprot.org/citations/37267956 | http://purl.uniprot.org/core/author | "Squire E."xsd:string |
http://purl.uniprot.org/citations/37267956 | http://purl.uniprot.org/core/date | "2023"xsd:gYear |
http://purl.uniprot.org/citations/37267956 | http://purl.uniprot.org/core/name | "Cell Metab"xsd:string |