| http://purl.uniprot.org/citations/37440281 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/37440281 | http://www.w3.org/2000/01/rdf-schema#comment | "ADAPTOR-ASSOCIATED PROTEIN KINASE1 (AAK1) is a known regulator of clathrin-mediated endocytosis in mammals. Human AAK1 phosphorylates the μ2 subunit of the ADAPTOR PROTEIN-2 (AP-2) complex (AP2M) and plays important roles in cell differentiation and development. Previous interactome studies discovered the association of AAK1 with AP-2 in Arabidopsis (Arabidopsis thaliana), but its function was unclear. Here, genetic analysis revealed that the Arabidopsis aak1 and ap2m mutants both displayed altered root tropic growth, including impaired touch- and gravity-sensing responses. In Arabidopsis, AAK1-phosphorylated AP2M on Thr-163, and expression of the phospho-null version of AP2M in the ap2m mutant led to an aak1-like phenotype, whereas the phospho-mimic forms of AP2M rescued the aak1 mutant. In addition, we found that the AAK1-dependent phosphorylation state of AP2M modulates the frequency distribution of endocytosis. Our data indicate that the phosphorylation of AP2M on Thr-163 by AAK1 fine-tunes endocytosis in the Arabidopsis root to control its tropic growth."xsd:string |
| http://purl.uniprot.org/citations/37440281 | http://purl.org/dc/terms/identifier | "doi:10.1093/plcell/koad141"xsd:string |
| http://purl.uniprot.org/citations/37440281 | http://purl.uniprot.org/core/author | "Russinova E."xsd:string |
| http://purl.uniprot.org/citations/37440281 | http://purl.uniprot.org/core/author | "Zhao X."xsd:string |
| http://purl.uniprot.org/citations/37440281 | http://purl.uniprot.org/core/author | "Wang P."xsd:string |
| http://purl.uniprot.org/citations/37440281 | http://purl.uniprot.org/core/author | "De Smet I."xsd:string |
| http://purl.uniprot.org/citations/37440281 | http://purl.uniprot.org/core/author | "Vu L.D."xsd:string |
| http://purl.uniprot.org/citations/37440281 | http://purl.uniprot.org/core/author | "Siao W."xsd:string |
| http://purl.uniprot.org/citations/37440281 | http://purl.uniprot.org/core/date | "2023"xsd:gYear |
| http://purl.uniprot.org/citations/37440281 | http://purl.uniprot.org/core/name | "Plant Cell"xsd:string |
| http://purl.uniprot.org/citations/37440281 | http://purl.uniprot.org/core/pages | "3504-3521"xsd:string |
| http://purl.uniprot.org/citations/37440281 | http://purl.uniprot.org/core/title | "Phosphorylation of ADAPTOR PROTEIN-2 mu-adaptin by ADAPTOR-ASSOCIATED KINASE1 regulates the tropic growth of Arabidopsis roots."xsd:string |
| http://purl.uniprot.org/citations/37440281 | http://purl.uniprot.org/core/volume | "35"xsd:string |
| http://purl.uniprot.org/citations/37440281 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/37440281 |
| http://purl.uniprot.org/citations/37440281 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/37440281 |
| http://purl.uniprot.org/uniprot/#_A0A178VTB4-mappedCitation-37440281 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/37440281 |
| http://purl.uniprot.org/uniprot/#_F4KHJ7-mappedCitation-37440281 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/37440281 |
| http://purl.uniprot.org/uniprot/#_A0A178UQZ5-mappedCitation-37440281 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/37440281 |
| http://purl.uniprot.org/uniprot/#_O23140-mappedCitation-37440281 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/37440281 |
| http://purl.uniprot.org/uniprot/#_O50071-mappedCitation-37440281 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/37440281 |
| http://purl.uniprot.org/uniprot/#_Q8H0Z0-mappedCitation-37440281 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/37440281 |
| http://purl.uniprot.org/uniprot/A0A178VTB4 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/37440281 |
| http://purl.uniprot.org/uniprot/Q8H0Z0 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/37440281 |
| http://purl.uniprot.org/uniprot/F4KHJ7 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/37440281 |