| http://purl.uniprot.org/citations/37526610 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/37526610 | http://www.w3.org/2000/01/rdf-schema#comment | "Drosophila is an important model for studying heart development and disease. Yet, single-cell transcriptomic data of its developing heart have not been performed. Here, we report single-cell profiling of the entire fly heart using ∼3000 Hand-GFP embryos collected at five consecutive developmental stages, ranging from bilateral migrating rows of cardiac progenitors to a fused heart tube. The data revealed six distinct cardiac cell types in the embryonic fly heart: cardioblasts, both Svp+ and Tin+ subtypes; and five types of pericardial cell (PC) that can be distinguished by four key transcription factors (Eve, Odd, Ct and Tin) and include the newly described end of the line PC. Notably, the embryonic fly heart combines transcriptional signatures of the mammalian first and second heart fields. Using unique markers for each heart cell type, we defined their number and location during heart development to build a comprehensive 3D cell map. These data provide a resource to track the expression of any gene in the developing fly heart, which can serve as a reference to study genetic perturbations and cardiac diseases."xsd:string |
| http://purl.uniprot.org/citations/37526610 | http://purl.org/dc/terms/identifier | "doi:10.1242/dev.201936"xsd:string |
| http://purl.uniprot.org/citations/37526610 | http://purl.uniprot.org/core/author | "Fu Y."xsd:string |
| http://purl.uniprot.org/citations/37526610 | http://purl.uniprot.org/core/author | "Huang X."xsd:string |
| http://purl.uniprot.org/citations/37526610 | http://purl.uniprot.org/core/author | "Lee H."xsd:string |
| http://purl.uniprot.org/citations/37526610 | http://purl.uniprot.org/core/author | "Zhao Y."xsd:string |
| http://purl.uniprot.org/citations/37526610 | http://purl.uniprot.org/core/author | "Yang W."xsd:string |
| http://purl.uniprot.org/citations/37526610 | http://purl.uniprot.org/core/author | "Han Z."xsd:string |
| http://purl.uniprot.org/citations/37526610 | http://purl.uniprot.org/core/author | "van de Leemput J."xsd:string |
| http://purl.uniprot.org/citations/37526610 | http://purl.uniprot.org/core/date | "2023"xsd:gYear |
| http://purl.uniprot.org/citations/37526610 | http://purl.uniprot.org/core/name | "Development"xsd:string |
| http://purl.uniprot.org/citations/37526610 | http://purl.uniprot.org/core/pages | "dev201936"xsd:string |
| http://purl.uniprot.org/citations/37526610 | http://purl.uniprot.org/core/title | "Single-cell profiling of the developing embryonic heart in Drosophila."xsd:string |
| http://purl.uniprot.org/citations/37526610 | http://purl.uniprot.org/core/volume | "150"xsd:string |
| http://purl.uniprot.org/citations/37526610 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/37526610 |
| http://purl.uniprot.org/citations/37526610 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/37526610 |
| http://purl.uniprot.org/uniprot/#_A0A0B4KFN3-mappedCitation-37526610 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/37526610 |
| http://purl.uniprot.org/uniprot/#_A0A0B4KFQ2-mappedCitation-37526610 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/37526610 |
| http://purl.uniprot.org/uniprot/#_A0A0B4KEQ1-mappedCitation-37526610 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/37526610 |
| http://purl.uniprot.org/uniprot/#_A0A0B4K711-mappedCitation-37526610 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/37526610 |
| http://purl.uniprot.org/uniprot/#_D2NUH8-mappedCitation-37526610 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/37526610 |
| http://purl.uniprot.org/uniprot/#_D2NUK9-mappedCitation-37526610 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/37526610 |
| http://purl.uniprot.org/uniprot/#_E1JHB6-mappedCitation-37526610 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/37526610 |
| http://purl.uniprot.org/uniprot/#_E1JHB7-mappedCitation-37526610 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/37526610 |