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http://purl.uniprot.org/citations/37542031http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/37542031http://www.w3.org/2000/01/rdf-schema#comment"Robust oxygenic photosynthesis requires a suite of accessory factors to ensure efficient assembly and repair of the oxygen-evolving photosystem two (PSII) complex. The highly conserved Ycf48 assembly factor binds to the newly synthesized D1 reaction center polypeptide and promotes the initial steps of PSII assembly, but its binding site is unclear. Here we use cryo-electron microscopy to determine the structure of a cyanobacterial PSII D1/D2 reaction center assembly complex with Ycf48 attached. Ycf48, a 7-bladed beta propeller, binds to the amino-acid residues of D1 that ultimately ligate the water-oxidising Mn4CaO5 cluster, thereby preventing the premature binding of Mn2+ and Ca2+ ions and protecting the site from damage. Interactions with D2 help explain how Ycf48 promotes assembly of the D1/D2 complex. Overall, our work provides valuable insights into the early stages of PSII assembly and the structural changes that create the binding site for the Mn4CaO5 cluster."xsd:string
http://purl.uniprot.org/citations/37542031http://purl.org/dc/terms/identifier"doi:10.1038/s41467-023-40388-6"xsd:string
http://purl.uniprot.org/citations/37542031http://purl.uniprot.org/core/author"Knoppova J."xsd:string
http://purl.uniprot.org/citations/37542031http://purl.uniprot.org/core/author"Komenda J."xsd:string
http://purl.uniprot.org/citations/37542031http://purl.uniprot.org/core/author"Murray J.W."xsd:string
http://purl.uniprot.org/citations/37542031http://purl.uniprot.org/core/author"Nixon P.J."xsd:string
http://purl.uniprot.org/citations/37542031http://purl.uniprot.org/core/author"Sobotka R."xsd:string
http://purl.uniprot.org/citations/37542031http://purl.uniprot.org/core/author"Zhao Z."xsd:string
http://purl.uniprot.org/citations/37542031http://purl.uniprot.org/core/author"Sazanov L.A."xsd:string
http://purl.uniprot.org/citations/37542031http://purl.uniprot.org/core/author"Vercellino I."xsd:string
http://purl.uniprot.org/citations/37542031http://purl.uniprot.org/core/date"2023"xsd:gYear
http://purl.uniprot.org/citations/37542031http://purl.uniprot.org/core/name"Nat Commun"xsd:string
http://purl.uniprot.org/citations/37542031http://purl.uniprot.org/core/pages"4681"xsd:string
http://purl.uniprot.org/citations/37542031http://purl.uniprot.org/core/title"The Ycf48 accessory factor occupies the site of the oxygen-evolving manganese cluster during photosystem II biogenesis."xsd:string
http://purl.uniprot.org/citations/37542031http://purl.uniprot.org/core/volume"14"xsd:string
http://purl.uniprot.org/citations/37542031http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/37542031
http://purl.uniprot.org/citations/37542031http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/37542031
http://purl.uniprot.org/uniprot/#_P12975-mappedCitation-37542031http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/37542031
http://purl.uniprot.org/uniprot/#_P29254-mappedCitation-37542031http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/37542031
http://purl.uniprot.org/uniprot/#_P29255-mappedCitation-37542031http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/37542031
http://purl.uniprot.org/uniprot/#_P29256-mappedCitation-37542031http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/37542031
http://purl.uniprot.org/uniprot/#_P37277-mappedCitation-37542031http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/37542031
http://purl.uniprot.org/uniprot/#_P09190-mappedCitation-37542031http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/37542031
http://purl.uniprot.org/uniprot/#_P09191-mappedCitation-37542031http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/37542031