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http://purl.uniprot.org/citations/37624694http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/37624694http://www.w3.org/2000/01/rdf-schema#comment"The superior colliculus (SC) is a sensorimotor structure in the midbrain that integrates input from multiple sensory modalities to initiate motor commands. It undergoes well-characterized steps of circuit assembly during development, rendering the mouse SC a popular model to study establishment of neural connectivity. Here we perform single-nucleus RNA-sequencing analysis of the mouse SC isolated at various developmental time points. Our study provides a transcriptomic landscape of the cell types that comprise the SC across murine development with particular emphasis on neuronal heterogeneity. We report a repertoire of genes differentially expressed across the different postnatal ages, many of which are known to regulate axon guidance and synapse formation. Using these data, we find that Pax7 expression is restricted to a subset of GABAergic neurons. Our data provide a valuable resource for interrogating the mechanisms of circuit development and identifying markers for manipulating specific SC neuronal populations and circuits."xsd:string
http://purl.uniprot.org/citations/37624694http://purl.org/dc/terms/identifier"doi:10.1016/j.celrep.2023.113037"xsd:string
http://purl.uniprot.org/citations/37624694http://purl.uniprot.org/core/author"Choi J.S."xsd:string
http://purl.uniprot.org/citations/37624694http://purl.uniprot.org/core/author"Levay K."xsd:string
http://purl.uniprot.org/citations/37624694http://purl.uniprot.org/core/author"Park K.K."xsd:string
http://purl.uniprot.org/citations/37624694http://purl.uniprot.org/core/author"Catanuto P."xsd:string
http://purl.uniprot.org/citations/37624694http://purl.uniprot.org/core/author"Beckedorff F."xsd:string
http://purl.uniprot.org/citations/37624694http://purl.uniprot.org/core/author"Ayupe A.C."xsd:string
http://purl.uniprot.org/citations/37624694http://purl.uniprot.org/core/author"McCartan R."xsd:string
http://purl.uniprot.org/citations/37624694http://purl.uniprot.org/core/date"2023"xsd:gYear
http://purl.uniprot.org/citations/37624694http://purl.uniprot.org/core/name"Cell Rep"xsd:string
http://purl.uniprot.org/citations/37624694http://purl.uniprot.org/core/pages"113037"xsd:string
http://purl.uniprot.org/citations/37624694http://purl.uniprot.org/core/title"Single-nucleus RNA sequencing of developing superior colliculus identifies neuronal diversity and candidate mediators of circuit assembly."xsd:string
http://purl.uniprot.org/citations/37624694http://purl.uniprot.org/core/volume"42"xsd:string
http://purl.uniprot.org/citations/37624694http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/37624694
http://purl.uniprot.org/citations/37624694http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/37624694
http://purl.uniprot.org/uniprot/#_A0A0R4J0A6-mappedCitation-37624694http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/37624694
http://purl.uniprot.org/uniprot/#_A0A097BVN3-mappedCitation-37624694http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/37624694
http://purl.uniprot.org/uniprot/#_A0A140LHC9-mappedCitation-37624694http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/37624694
http://purl.uniprot.org/uniprot/#_D3YWL3-mappedCitation-37624694http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/37624694
http://purl.uniprot.org/uniprot/#_D3Z0J7-mappedCitation-37624694http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/37624694
http://purl.uniprot.org/uniprot/#_E0CYH9-mappedCitation-37624694http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/37624694
http://purl.uniprot.org/uniprot/#_A0A1C7ZN00-mappedCitation-37624694http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/37624694
http://purl.uniprot.org/uniprot/#_A0A7R7YCL1-mappedCitation-37624694http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/37624694