RDF/XMLNTriplesTurtleShow queryShare
SubjectPredicateObject
http://purl.uniprot.org/citations/3769923http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/3769923http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/3769923http://www.w3.org/2000/01/rdf-schema#comment"Epidermin is a large peptide antibiotic, which is synthesized in the ribosome via a precursor protein, followed by enzymatic modifications. It was isolated from the culture filtrate of Staphylococcus epidermidis Tü 3298 by adsorption on Amberlite XAD-8. The basic heneicosapeptide amide was chromatographed on Sephadex LH-20 and purified to homogeneity via multiplicative counter-current distributions in one acidic and one neutral system. Tryptic digestion gave the soluble N-terminal fragment epidermin-(1-13)-peptide (P1) and the insoluble C-terminal fragment 2-oxobutyryl-epidermin-(15-21)-peptide amide (P2), each possessing two sulfide ring systems. The heterodetic rings consisted of meso-lanthionine and (2S,3S, 6R)-3-methyllanthionine (P1), meso-lanthionine and C-terminally the new amino acid S-(2-aminovinyl)-D-cysteine (P2). The complex sequence was elucidated via a combination of desulfurization with Raney nickel, enzymatic and acidolytic degradations, gas-phase sequencing, fast-atom bombardment and field-desorption mass spectrometry and NMR spectroscopy."xsd:string
http://purl.uniprot.org/citations/3769923http://purl.org/dc/terms/identifier"doi:10.1111/j.1432-1033.1986.tb09933.x"xsd:string
http://purl.uniprot.org/citations/3769923http://purl.org/dc/terms/identifier"doi:10.1111/j.1432-1033.1986.tb09933.x"xsd:string
http://purl.uniprot.org/citations/3769923http://purl.uniprot.org/core/author"Jung G."xsd:string
http://purl.uniprot.org/citations/3769923http://purl.uniprot.org/core/author"Jung G."xsd:string
http://purl.uniprot.org/citations/3769923http://purl.uniprot.org/core/author"Schneider U."xsd:string
http://purl.uniprot.org/citations/3769923http://purl.uniprot.org/core/author"Schneider U."xsd:string
http://purl.uniprot.org/citations/3769923http://purl.uniprot.org/core/author"Allgaier H."xsd:string
http://purl.uniprot.org/citations/3769923http://purl.uniprot.org/core/author"Allgaier H."xsd:string
http://purl.uniprot.org/citations/3769923http://purl.uniprot.org/core/author"Werner R.G."xsd:string
http://purl.uniprot.org/citations/3769923http://purl.uniprot.org/core/author"Werner R.G."xsd:string
http://purl.uniprot.org/citations/3769923http://purl.uniprot.org/core/author"Zahner H."xsd:string
http://purl.uniprot.org/citations/3769923http://purl.uniprot.org/core/author"Zahner H."xsd:string
http://purl.uniprot.org/citations/3769923http://purl.uniprot.org/core/date"1986"xsd:gYear
http://purl.uniprot.org/citations/3769923http://purl.uniprot.org/core/date"1986"xsd:gYear
http://purl.uniprot.org/citations/3769923http://purl.uniprot.org/core/name"Eur. J. Biochem."xsd:string
http://purl.uniprot.org/citations/3769923http://purl.uniprot.org/core/name"Eur. J. Biochem."xsd:string
http://purl.uniprot.org/citations/3769923http://purl.uniprot.org/core/pages"9-22"xsd:string
http://purl.uniprot.org/citations/3769923http://purl.uniprot.org/core/pages"9-22"xsd:string
http://purl.uniprot.org/citations/3769923http://purl.uniprot.org/core/title"Epidermin: sequencing of a heterodetic tetracyclic 21-peptide amide antibiotic."xsd:string
http://purl.uniprot.org/citations/3769923http://purl.uniprot.org/core/title"Epidermin: sequencing of a heterodetic tetracyclic 21-peptide amide antibiotic."xsd:string
http://purl.uniprot.org/citations/3769923http://purl.uniprot.org/core/volume"160"xsd:string
http://purl.uniprot.org/citations/3769923http://purl.uniprot.org/core/volume"160"xsd:string