http://purl.uniprot.org/citations/3769923 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/3769923 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/3769923 | http://www.w3.org/2000/01/rdf-schema#comment | "Epidermin is a large peptide antibiotic, which is synthesized in the ribosome via a precursor protein, followed by enzymatic modifications. It was isolated from the culture filtrate of Staphylococcus epidermidis Tü 3298 by adsorption on Amberlite XAD-8. The basic heneicosapeptide amide was chromatographed on Sephadex LH-20 and purified to homogeneity via multiplicative counter-current distributions in one acidic and one neutral system. Tryptic digestion gave the soluble N-terminal fragment epidermin-(1-13)-peptide (P1) and the insoluble C-terminal fragment 2-oxobutyryl-epidermin-(15-21)-peptide amide (P2), each possessing two sulfide ring systems. The heterodetic rings consisted of meso-lanthionine and (2S,3S, 6R)-3-methyllanthionine (P1), meso-lanthionine and C-terminally the new amino acid S-(2-aminovinyl)-D-cysteine (P2). The complex sequence was elucidated via a combination of desulfurization with Raney nickel, enzymatic and acidolytic degradations, gas-phase sequencing, fast-atom bombardment and field-desorption mass spectrometry and NMR spectroscopy."xsd:string |
http://purl.uniprot.org/citations/3769923 | http://purl.org/dc/terms/identifier | "doi:10.1111/j.1432-1033.1986.tb09933.x"xsd:string |
http://purl.uniprot.org/citations/3769923 | http://purl.org/dc/terms/identifier | "doi:10.1111/j.1432-1033.1986.tb09933.x"xsd:string |
http://purl.uniprot.org/citations/3769923 | http://purl.uniprot.org/core/author | "Jung G."xsd:string |
http://purl.uniprot.org/citations/3769923 | http://purl.uniprot.org/core/author | "Jung G."xsd:string |
http://purl.uniprot.org/citations/3769923 | http://purl.uniprot.org/core/author | "Schneider U."xsd:string |
http://purl.uniprot.org/citations/3769923 | http://purl.uniprot.org/core/author | "Schneider U."xsd:string |
http://purl.uniprot.org/citations/3769923 | http://purl.uniprot.org/core/author | "Allgaier H."xsd:string |
http://purl.uniprot.org/citations/3769923 | http://purl.uniprot.org/core/author | "Allgaier H."xsd:string |
http://purl.uniprot.org/citations/3769923 | http://purl.uniprot.org/core/author | "Werner R.G."xsd:string |
http://purl.uniprot.org/citations/3769923 | http://purl.uniprot.org/core/author | "Werner R.G."xsd:string |
http://purl.uniprot.org/citations/3769923 | http://purl.uniprot.org/core/author | "Zahner H."xsd:string |
http://purl.uniprot.org/citations/3769923 | http://purl.uniprot.org/core/author | "Zahner H."xsd:string |
http://purl.uniprot.org/citations/3769923 | http://purl.uniprot.org/core/date | "1986"xsd:gYear |
http://purl.uniprot.org/citations/3769923 | http://purl.uniprot.org/core/date | "1986"xsd:gYear |
http://purl.uniprot.org/citations/3769923 | http://purl.uniprot.org/core/name | "Eur. J. Biochem."xsd:string |
http://purl.uniprot.org/citations/3769923 | http://purl.uniprot.org/core/name | "Eur. J. Biochem."xsd:string |
http://purl.uniprot.org/citations/3769923 | http://purl.uniprot.org/core/pages | "9-22"xsd:string |
http://purl.uniprot.org/citations/3769923 | http://purl.uniprot.org/core/pages | "9-22"xsd:string |
http://purl.uniprot.org/citations/3769923 | http://purl.uniprot.org/core/title | "Epidermin: sequencing of a heterodetic tetracyclic 21-peptide amide antibiotic."xsd:string |
http://purl.uniprot.org/citations/3769923 | http://purl.uniprot.org/core/title | "Epidermin: sequencing of a heterodetic tetracyclic 21-peptide amide antibiotic."xsd:string |
http://purl.uniprot.org/citations/3769923 | http://purl.uniprot.org/core/volume | "160"xsd:string |
http://purl.uniprot.org/citations/3769923 | http://purl.uniprot.org/core/volume | "160"xsd:string |