DESCRIBE <http://purl.uniprot.org/citations/37821801>

Subject	Predicate	Object
http://purl.uniprot.org/citations/37821801	http://www.w3.org/1999/02/22-rdf-syntax-ns#type	http://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/37821801	http://www.w3.org/2000/01/rdf-schema#comment	" Background Replication factor C subunit 2 (RFC2) participates in the growth and metastasis of various malignancies. Our study investigated the roles of RFC2 in colorectal cancer (CRC). Results RFC2 expression was upregulated in CRC tissues and cells. High RFC2 expression was associated with poor prognosis. Knockdown RFC2 inhibited proliferation, induced apoptosis, and suppressed migration and invasion of CRC cells. CREB5 was a transcription factor of RFC2, and CREB5 knockdown suppressed RFC2 expression. Furthermore, RFC2 promoted aerobic glycolysis and MET/PI3K/AKT/mTOR pathway. Conclusion RFC2 promoted the progression of CRC cells via activating aerobic glycolysis and the MET/PI3K/AKT/mTOR pathway."xsd:string
http://purl.uniprot.org/citations/37821801	http://purl.org/dc/terms/identifier	"doi:10.1186/s12876-023-02984-0"xsd:string
http://purl.uniprot.org/citations/37821801	http://purl.uniprot.org/core/author	"Zhang M."xsd:string
http://purl.uniprot.org/citations/37821801	http://purl.uniprot.org/core/author	"Lou F."xsd:string
http://purl.uniprot.org/citations/37821801	http://purl.uniprot.org/core/date	"2023"xsd:gYear
http://purl.uniprot.org/citations/37821801	http://purl.uniprot.org/core/name	"BMC Gastroenterol"xsd:string
http://purl.uniprot.org/citations/37821801	http://purl.uniprot.org/core/pages	"353"xsd:string
http://purl.uniprot.org/citations/37821801	http://purl.uniprot.org/core/title	"RFC2 promotes aerobic glycolysis and progression of colorectal cancer."xsd:string
http://purl.uniprot.org/citations/37821801	http://purl.uniprot.org/core/volume	"23"xsd:string
http://purl.uniprot.org/citations/37821801	http://www.w3.org/2004/02/skos/core#exactMatch	http://purl.uniprot.org/pubmed/37821801
http://purl.uniprot.org/citations/37821801	http://xmlns.com/foaf/0.1/primaryTopicOf	https://pubmed.ncbi.nlm.nih.gov/37821801
http://purl.uniprot.org/uniprot/#_A0A087WVY3-mappedCitation-37821801	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/37821801
http://purl.uniprot.org/uniprot/#_B5BUD2-mappedCitation-37821801	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/37821801
http://purl.uniprot.org/uniprot/#_P35250-mappedCitation-37821801	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/37821801
http://purl.uniprot.org/uniprot/#_Q75MT5-mappedCitation-37821801	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/37821801
http://purl.uniprot.org/uniprot/Q75MT5	http://purl.uniprot.org/core/mappedCitation	http://purl.uniprot.org/citations/37821801
http://purl.uniprot.org/uniprot/P35250	http://purl.uniprot.org/core/mappedCitation	http://purl.uniprot.org/citations/37821801
http://purl.uniprot.org/uniprot/A0A087WVY3	http://purl.uniprot.org/core/mappedCitation	http://purl.uniprot.org/citations/37821801
http://purl.uniprot.org/uniprot/B5BUD2	http://purl.uniprot.org/core/mappedCitation	http://purl.uniprot.org/citations/37821801