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http://purl.uniprot.org/citations/37916147http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/37916147http://www.w3.org/2000/01/rdf-schema#comment"

Aims

To explore the relationship between plasma leucine-rich α-2-glycoprotein 1 (LRG1) level and the degree of urinary albumin excretion in patients with type 2 diabetes.

Methods

We evaluated 332 patients with type 2 diabetes in a cross-sectional study.

Result

The plasma LRG1 level differed significantly according to the quartiles of urinary albumin excretion (Q1 [<7.7 mg/g], 17.1 μg/mL; Q2 [7.7-15.0 mg/g], 17.5 μg/mL; Q3 [15.1-61.4 mg/g], 18.6 μg/mL; Q4 [≥61.5 mg/g], 22.3 μg/mL; p for trend = 0.003) under adjustment with other covariates. A positive correlation was found between plasma LRG1 level and urinary albumin excretion (ρ = 0.256, p <0.001). According to a multivariate model, the association between LRG1 and urinary albumin excretion remained significant, under adjustment for confounding factors (β = 0.285, p <0.001).

Conclusion

Plasma LRG1 level was independently associated with urinary albumin excretion in patients with type 2 diabetes. This study suggests that LRG1 may be associated with increased excretion of urinary albumin in the early stages of diabetic nephropathy."xsd:string
http://purl.uniprot.org/citations/37916147http://purl.org/dc/terms/identifier"doi:10.3389/fendo.2023.1232021"xsd:string
http://purl.uniprot.org/citations/37916147http://purl.uniprot.org/core/author"Park S.Y."xsd:string
http://purl.uniprot.org/citations/37916147http://purl.uniprot.org/core/author"Cho D.H."xsd:string
http://purl.uniprot.org/citations/37916147http://purl.uniprot.org/core/author"Chung M.Y."xsd:string
http://purl.uniprot.org/citations/37916147http://purl.uniprot.org/core/author"Chung D.J."xsd:string
http://purl.uniprot.org/citations/37916147http://purl.uniprot.org/core/author"Chung J.O."xsd:string
http://purl.uniprot.org/citations/37916147http://purl.uniprot.org/core/date"2023"xsd:gYear
http://purl.uniprot.org/citations/37916147http://purl.uniprot.org/core/name"Front Endocrinol (Lausanne)"xsd:string
http://purl.uniprot.org/citations/37916147http://purl.uniprot.org/core/pages"1232021"xsd:string
http://purl.uniprot.org/citations/37916147http://purl.uniprot.org/core/title"Relationship between plasma leucine-rich alpha-2-glycoprotein 1 and urinary albumin excretion in patients with type 2 diabetes."xsd:string
http://purl.uniprot.org/citations/37916147http://purl.uniprot.org/core/volume"14"xsd:string
http://purl.uniprot.org/citations/37916147http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/37916147
http://purl.uniprot.org/citations/37916147http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/37916147
http://purl.uniprot.org/uniprot/#_B4E1I8-mappedCitation-37916147http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/37916147
http://purl.uniprot.org/uniprot/#_P02750-mappedCitation-37916147http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/37916147
http://purl.uniprot.org/uniprot/#_Q68CK4-mappedCitation-37916147http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/37916147
http://purl.uniprot.org/uniprot/P02750http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/37916147
http://purl.uniprot.org/uniprot/B4E1I8http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/37916147
http://purl.uniprot.org/uniprot/Q68CK4http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/37916147