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http://purl.uniprot.org/citations/38086445http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/38086445http://www.w3.org/2000/01/rdf-schema#comment"The cation-independent mannose 6-phosphate receptor (CI-M6PR) is a ubiquitous transmembrane receptor whose main intracellular role is to direct enzymes carrying mannose 6-phosphate moieties to lysosomal compartments. Recently, the small membrane-bound portion of this receptor has appeared to be implicated in numerous pathophysiological processes. This review presents an overview of the main ligand partners and the roles of CI-M6PR in lysosomal storage diseases, neurology, immunology and cancer fields. Moreover, this membrane receptor has already been noted for its strong potential in therapeutic applications thanks to its cellular internalization activity and its ability to address pathogenic factors to lysosomes for degradation. A number of therapeutic delivery approaches using CI-M6PR, in particular with enzymes, antibodies or nanoparticles, are currently being proposed."xsd:string
http://purl.uniprot.org/citations/38086445http://purl.org/dc/terms/identifier"doi:10.1016/j.jconrel.2023.12.014"xsd:string
http://purl.uniprot.org/citations/38086445http://purl.uniprot.org/core/author"Garcia M."xsd:string
http://purl.uniprot.org/citations/38086445http://purl.uniprot.org/core/author"Maynadier M."xsd:string
http://purl.uniprot.org/citations/38086445http://purl.uniprot.org/core/author"Gauthier C."xsd:string
http://purl.uniprot.org/citations/38086445http://purl.uniprot.org/core/author"El Cheikh K."xsd:string
http://purl.uniprot.org/citations/38086445http://purl.uniprot.org/core/author"Basile I."xsd:string
http://purl.uniprot.org/citations/38086445http://purl.uniprot.org/core/author"Gary-Bobo M."xsd:string
http://purl.uniprot.org/citations/38086445http://purl.uniprot.org/core/author"Daurat M."xsd:string
http://purl.uniprot.org/citations/38086445http://purl.uniprot.org/core/author"Morere A."xsd:string
http://purl.uniprot.org/citations/38086445http://purl.uniprot.org/core/author"Morere E."xsd:string
http://purl.uniprot.org/citations/38086445http://purl.uniprot.org/core/date"2024"xsd:gYear
http://purl.uniprot.org/citations/38086445http://purl.uniprot.org/core/name"J Control Release"xsd:string
http://purl.uniprot.org/citations/38086445http://purl.uniprot.org/core/pages"759-772"xsd:string
http://purl.uniprot.org/citations/38086445http://purl.uniprot.org/core/title"Cation-independent mannose 6-phosphate receptor: From roles and functions to targeted therapies."xsd:string
http://purl.uniprot.org/citations/38086445http://purl.uniprot.org/core/volume"365"xsd:string
http://purl.uniprot.org/citations/38086445http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/38086445
http://purl.uniprot.org/citations/38086445http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/38086445
http://purl.uniprot.org/uniprot/#_A0N9R6-mappedCitation-38086445http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/38086445
http://purl.uniprot.org/uniprot/#_A0N9R7-mappedCitation-38086445http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/38086445
http://purl.uniprot.org/uniprot/#_A0N9R9-mappedCitation-38086445http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/38086445
http://purl.uniprot.org/uniprot/#_B4DUY7-mappedCitation-38086445http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/38086445
http://purl.uniprot.org/uniprot/#_Q13660-mappedCitation-38086445http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/38086445
http://purl.uniprot.org/uniprot/#_Q13661-mappedCitation-38086445http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/38086445