| http://purl.uniprot.org/citations/38088874 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/38088874 | http://www.w3.org/2000/01/rdf-schema#comment | "The capping of barbed filament ends is a fundamental mechanism for actin regulation. Capping protein controls filament growth and actin turnover in cells by binding to the barbed ends of the filaments with high affinity and slow off-rate. The interaction between capping protein and actin is regulated by capping protein interaction (CPI) motif proteins. We identified a novel CPI motif protein, Bsp1, which is involved in cytokinesis and endocytosis in budding yeast. We demonstrate that Bsp1 is an actin binding protein with a high affinity for capping protein via its CPI motif. In cells, Bsp1 regulates capping protein at endocytic sites and is a major recruiter of capping protein to the cytokinetic actin ring. Lastly, we define Bsp1-related proteins as a distinct fungi-specific CPI protein group. Our results suggest that Bsp1 promotes actin filament capping by the capping protein. This study establishes Bsp1 as a new capping protein regulator and promising candidate to regulate actin networks in fungi."xsd:string |
| http://purl.uniprot.org/citations/38088874 | http://purl.org/dc/terms/identifier | "doi:10.1091/mbc.e23-10-0391"xsd:string |
| http://purl.uniprot.org/citations/38088874 | http://purl.uniprot.org/core/author | "Kaksonen M."xsd:string |
| http://purl.uniprot.org/citations/38088874 | http://purl.uniprot.org/core/author | "Toret C.P."xsd:string |
| http://purl.uniprot.org/citations/38088874 | http://purl.uniprot.org/core/author | "Hakala M."xsd:string |
| http://purl.uniprot.org/citations/38088874 | http://purl.uniprot.org/core/author | "Hummel D.R."xsd:string |
| http://purl.uniprot.org/citations/38088874 | http://purl.uniprot.org/core/date | "2024"xsd:gYear |
| http://purl.uniprot.org/citations/38088874 | http://purl.uniprot.org/core/name | "Mol Biol Cell"xsd:string |
| http://purl.uniprot.org/citations/38088874 | http://purl.uniprot.org/core/pages | "br6"xsd:string |
| http://purl.uniprot.org/citations/38088874 | http://purl.uniprot.org/core/title | "Bsp1, a fungal CPI motif protein, regulates actin filament capping in endocytosis and cytokinesis."xsd:string |
| http://purl.uniprot.org/citations/38088874 | http://purl.uniprot.org/core/volume | "35"xsd:string |
| http://purl.uniprot.org/citations/38088874 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/38088874 |
| http://purl.uniprot.org/citations/38088874 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/38088874 |
| http://purl.uniprot.org/uniprot/#_A0A8H4BUL3-mappedCitation-38088874 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/38088874 |
| http://purl.uniprot.org/uniprot/#_Q06604-mappedCitation-38088874 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/38088874 |
| http://purl.uniprot.org/uniprot/A0A8H4BUL3 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/38088874 |
| http://purl.uniprot.org/uniprot/Q06604 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/38088874 |