http://purl.uniprot.org/citations/38165573 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/38165573 | http://www.w3.org/2000/01/rdf-schema#comment | "The histone lysine demethylase 3 A (KDM3A) is vital for the regulation of cancer physiology and pathophysiology. The purpose of this study was to investigate the effect of KDM3A expression with triple-negative breast cancer (TNBC) invasion and metastasis. In our results, knockout of KDM3A in TNBC MDA-MB-231 cells promoted apoptosis and inhibited the proliferation, invasion and metastasis of MDA-MB-231 cells. In addition, we found that in vivo experiments indicated that the growth, invasion and metastasis of metastatic neoplasms were significantly inhibited by knockout of KDM3A in a TNBC metastasis model. These findings suggest that KDM3A may be a potential therapeutic target for the treatment and prevention of TNBC, providing a critical theoretical basis for the effective prevention or treatment of breast cancer disease."xsd:string |
http://purl.uniprot.org/citations/38165573 | http://purl.org/dc/terms/identifier | "doi:10.1007/s10735-023-10178-x"xsd:string |
http://purl.uniprot.org/citations/38165573 | http://purl.uniprot.org/core/author | "Han Y."xsd:string |
http://purl.uniprot.org/citations/38165573 | http://purl.uniprot.org/core/author | "Sun Y."xsd:string |
http://purl.uniprot.org/citations/38165573 | http://purl.uniprot.org/core/author | "Yao J."xsd:string |
http://purl.uniprot.org/citations/38165573 | http://purl.uniprot.org/core/author | "Maimaiti N."xsd:string |
http://purl.uniprot.org/citations/38165573 | http://purl.uniprot.org/core/date | "2024"xsd:gYear |
http://purl.uniprot.org/citations/38165573 | http://purl.uniprot.org/core/name | "J Mol Histol"xsd:string |
http://purl.uniprot.org/citations/38165573 | http://purl.uniprot.org/core/pages | "139-148"xsd:string |
http://purl.uniprot.org/citations/38165573 | http://purl.uniprot.org/core/title | "Knockout of KDM3A in MDA-MB-231 breast cancer cells inhibits tumor malignancy and promotes apoptosis."xsd:string |
http://purl.uniprot.org/citations/38165573 | http://purl.uniprot.org/core/volume | "55"xsd:string |
http://purl.uniprot.org/citations/38165573 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/38165573 |
http://purl.uniprot.org/citations/38165573 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/38165573 |
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http://purl.uniprot.org/uniprot/#_Q9Y4C1-mappedCitation-38165573 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/38165573 |
http://purl.uniprot.org/uniprot/Q9Y4C1 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/38165573 |
http://purl.uniprot.org/uniprot/B4E2H5 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/38165573 |