| http://purl.uniprot.org/citations/3818598 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/3818598 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/3818598 | http://www.w3.org/2000/01/rdf-schema#comment | "Two types of rat kininogen mRNAs exhibit marked differences in the regulation of their expressions. The two T kininogen (T) mRNAs considerably increase under acute inflammation conditions, although no such increase occurs in the high molecular weight and low molecular weight K kininogen (K) mRNAs encoded by the same gene. This investigation examines the sequences of the 5' portions of the K and the two T genes and analyzes transcription initiation sites and their utilization at differently regulated conditions of the K and T genes. The sequence analysis indicates that the K and the two T genes are extremely homologous at the 5' portions as well as the 5'-flanking regions of at least 1.0 kilobase pairs. The S1 nuclease and primer extension analyses show that both T and K mRNAs start with three sets of the homologous initiation sites, and the utilization of the two 3'-side initiation sites of the T genes markedly increases under inflammation conditions. In contrast, no such elevation is observed for the three initiation sites of the K gene. Thus, although the sequences involved as transcription initiation sites are extremely homologous, their utilizations in the expressions of the K and T genes are regulated differently under inflammation conditions."xsd:string |
| http://purl.uniprot.org/citations/3818598 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0021-9258(18)61660-6"xsd:string |
| http://purl.uniprot.org/citations/3818598 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0021-9258(18)61660-6"xsd:string |
| http://purl.uniprot.org/citations/3818598 | http://purl.uniprot.org/core/author | "Kitagawa H."xsd:string |
| http://purl.uniprot.org/citations/3818598 | http://purl.uniprot.org/core/author | "Miyata T."xsd:string |
| http://purl.uniprot.org/citations/3818598 | http://purl.uniprot.org/core/author | "Nakanishi S."xsd:string |
| http://purl.uniprot.org/citations/3818598 | http://purl.uniprot.org/core/author | "Nakanishi S."xsd:string |
| http://purl.uniprot.org/citations/3818598 | http://purl.uniprot.org/core/author | "Hayashida H."xsd:string |
| http://purl.uniprot.org/citations/3818598 | http://purl.uniprot.org/core/author | "Kitamura N."xsd:string |
| http://purl.uniprot.org/citations/3818598 | http://purl.uniprot.org/core/author | "Kitamura N."xsd:string |
| http://purl.uniprot.org/citations/3818598 | http://purl.uniprot.org/core/author | "Ohkubo H."xsd:string |
| http://purl.uniprot.org/citations/3818598 | http://purl.uniprot.org/core/author | "Ohkubo H."xsd:string |
| http://purl.uniprot.org/citations/3818598 | http://purl.uniprot.org/core/author | "Kageyama R."xsd:string |
| http://purl.uniprot.org/citations/3818598 | http://purl.uniprot.org/core/author | "Kageyama R."xsd:string |
| http://purl.uniprot.org/citations/3818598 | http://purl.uniprot.org/core/date | "1987"xsd:gYear |
| http://purl.uniprot.org/citations/3818598 | http://purl.uniprot.org/core/date | "1987"xsd:gYear |
| http://purl.uniprot.org/citations/3818598 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
| http://purl.uniprot.org/citations/3818598 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
| http://purl.uniprot.org/citations/3818598 | http://purl.uniprot.org/core/pages | "2345-2351"xsd:string |
| http://purl.uniprot.org/citations/3818598 | http://purl.uniprot.org/core/pages | "2345-2351"xsd:string |
| http://purl.uniprot.org/citations/3818598 | http://purl.uniprot.org/core/title | "Differing utilization of homologous transcription initiation sites of rat K and T kininogen genes under inflammation condition."xsd:string |
| http://purl.uniprot.org/citations/3818598 | http://purl.uniprot.org/core/title | "Differing utilization of homologous transcription initiation sites of rat K and T kininogen genes under inflammation condition."xsd:string |
| http://purl.uniprot.org/citations/3818598 | http://purl.uniprot.org/core/volume | "262"xsd:string |