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http://purl.uniprot.org/citations/38279497http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/38279497http://www.w3.org/2000/01/rdf-schema#comment"Long non-coding RNAs (lncRNAs) have been regarded as promising biomarkers in the regulation of various biological and pathological processes of non-small cell lung cancer (NSCLC). LncRNAITGA9-AS1 has been reported to be down-regulated in elderly patients with lung cancer, but how it may influence NSCLC remains to be identified. Therefore, we aim to explore the specific mechanism involving ITGA9-AS1 and ITGA9 in NSCLC. A functional assay was conducted to verify ITGA9-AS1's proliferative effects on NSCLC cells. Mechanism experiments with bioinformatics predictions were performed to explore the interaction of ITGA9-AS1 and ITGA9 in NSCLC cells. ITGA9-AS1 inhibited NSCLC cell proliferation while enhancing cell apoptosis. It up-regulated ITGA9 by competitively sponging miR-4765, and it stabilizedITGA9 mRNA by recruiting a RNA-binding protein (RBP)-HNRNPU (heterogeneous nuclear ribonucleoprotein U) in NSCLC cells. ITGA9-AS1 suppressed NSCLC progression by the up-regulation of ITGA9 via targeting miR-4765 and recruiting HNRNPU."xsd:string
http://purl.uniprot.org/citations/38279497http://purl.org/dc/terms/identifier"doi:10.14715/cmb/2023.69.14.4"xsd:string
http://purl.uniprot.org/citations/38279497http://purl.uniprot.org/core/author"Chen Y."xsd:string
http://purl.uniprot.org/citations/38279497http://purl.uniprot.org/core/author"Gu W."xsd:string
http://purl.uniprot.org/citations/38279497http://purl.uniprot.org/core/author"Liu W."xsd:string
http://purl.uniprot.org/citations/38279497http://purl.uniprot.org/core/author"Ma J."xsd:string
http://purl.uniprot.org/citations/38279497http://purl.uniprot.org/core/author"Tan Y."xsd:string
http://purl.uniprot.org/citations/38279497http://purl.uniprot.org/core/author"Yang Z."xsd:string
http://purl.uniprot.org/citations/38279497http://purl.uniprot.org/core/author"Zhang K."xsd:string
http://purl.uniprot.org/citations/38279497http://purl.uniprot.org/core/author"Liu K."xsd:string
http://purl.uniprot.org/citations/38279497http://purl.uniprot.org/core/author"Fang S."xsd:string
http://purl.uniprot.org/citations/38279497http://purl.uniprot.org/core/date"2023"xsd:gYear
http://purl.uniprot.org/citations/38279497http://purl.uniprot.org/core/name"Cell Mol Biol (Noisy-le-grand)"xsd:string
http://purl.uniprot.org/citations/38279497http://purl.uniprot.org/core/pages"22-28"xsd:string
http://purl.uniprot.org/citations/38279497http://purl.uniprot.org/core/title"ITGA9-AS1 up-regulates ITGA9 by targeting miR-4765 and recruiting HNRNPU to affect the proliferation and apoptosis of non-small cell lung cancer cells."xsd:string
http://purl.uniprot.org/citations/38279497http://purl.uniprot.org/core/volume"69"xsd:string
http://purl.uniprot.org/citations/38279497http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/38279497
http://purl.uniprot.org/citations/38279497http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/38279497
http://purl.uniprot.org/uniprot/#_L8E7C7-mappedCitation-38279497http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/38279497
http://purl.uniprot.org/uniprot/#_Q13797-mappedCitation-38279497http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/38279497
http://purl.uniprot.org/uniprot/#_Q8N6H6-mappedCitation-38279497http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/38279497
http://purl.uniprot.org/uniprot/Q8N6H6http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/38279497
http://purl.uniprot.org/uniprot/Q13797http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/38279497
http://purl.uniprot.org/uniprot/L8E7C7http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/38279497