| http://purl.uniprot.org/citations/3898070 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/3898070 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/3898070 | http://www.w3.org/2000/01/rdf-schema#comment | "The amino acid sequence of rabbit skeletal muscle heat-stable inhibitor of the cAMP-dependent protein kinase has been determined by microsequencing techniques. Proof of the structure involved a series of nonoverlapping tryptic fragments for primary identification of 86% of the amino acids. Complementary fragments generated by cleavage with chymotrypsin, Staphylococcus aureus V8 proteinase, and mast cell proteinase II contributed to proof of the structure. The inhibitor is a single polypeptide chain of 75 residues and has a molecular weight of 7829. It lacks tryptophan, proline, and sulfur-containing amino acids. The amino terminus of the inhibitor is blocked by an unidentified group. The amino-terminal region of the molecule contains the kinase inhibitory domain, and synthetic peptides based on the sequence of residues 11-30 are potent competitive inhibitors of the cAMP-dependent protein kinase [Scott, J. D., Fischer, E. H., Demaille, J. G. & Krebs, E. G. (1985) Proc. Natl. Acad. Sci. USA 82, 4379-4383]. Residues 14-22 show considerable homology to the "hinge-regions" of the regulatory subunits of the cAMP-dependent protein kinase. The remainder of the molecule shows no similarity to the known amino acid sequence of any protein."xsd:string |
| http://purl.uniprot.org/citations/3898070 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.82.17.5732"xsd:string |
| http://purl.uniprot.org/citations/3898070 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.82.17.5732"xsd:string |
| http://purl.uniprot.org/citations/3898070 | http://purl.uniprot.org/core/author | "Scott J.D."xsd:string |
| http://purl.uniprot.org/citations/3898070 | http://purl.uniprot.org/core/author | "Scott J.D."xsd:string |
| http://purl.uniprot.org/citations/3898070 | http://purl.uniprot.org/core/author | "Takio K."xsd:string |
| http://purl.uniprot.org/citations/3898070 | http://purl.uniprot.org/core/author | "Takio K."xsd:string |
| http://purl.uniprot.org/citations/3898070 | http://purl.uniprot.org/core/author | "Fischer E.H."xsd:string |
| http://purl.uniprot.org/citations/3898070 | http://purl.uniprot.org/core/author | "Fischer E.H."xsd:string |
| http://purl.uniprot.org/citations/3898070 | http://purl.uniprot.org/core/author | "Demaille J.G."xsd:string |
| http://purl.uniprot.org/citations/3898070 | http://purl.uniprot.org/core/author | "Demaille J.G."xsd:string |
| http://purl.uniprot.org/citations/3898070 | http://purl.uniprot.org/core/author | "Krebs E.G."xsd:string |
| http://purl.uniprot.org/citations/3898070 | http://purl.uniprot.org/core/author | "Krebs E.G."xsd:string |
| http://purl.uniprot.org/citations/3898070 | http://purl.uniprot.org/core/date | "1985"xsd:gYear |
| http://purl.uniprot.org/citations/3898070 | http://purl.uniprot.org/core/date | "1985"xsd:gYear |
| http://purl.uniprot.org/citations/3898070 | http://purl.uniprot.org/core/name | "Proc. Natl. Acad. Sci. U.S.A."xsd:string |
| http://purl.uniprot.org/citations/3898070 | http://purl.uniprot.org/core/name | "Proc. Natl. Acad. Sci. U.S.A."xsd:string |
| http://purl.uniprot.org/citations/3898070 | http://purl.uniprot.org/core/pages | "5732-5736"xsd:string |
| http://purl.uniprot.org/citations/3898070 | http://purl.uniprot.org/core/pages | "5732-5736"xsd:string |
| http://purl.uniprot.org/citations/3898070 | http://purl.uniprot.org/core/title | "Amino acid sequence of the heat-stable inhibitor of the cAMP-dependent protein kinase from rabbit skeletal muscle."xsd:string |
| http://purl.uniprot.org/citations/3898070 | http://purl.uniprot.org/core/title | "Amino acid sequence of the heat-stable inhibitor of the cAMP-dependent protein kinase from rabbit skeletal muscle."xsd:string |
| http://purl.uniprot.org/citations/3898070 | http://purl.uniprot.org/core/volume | "82"xsd:string |
| http://purl.uniprot.org/citations/3898070 | http://purl.uniprot.org/core/volume | "82"xsd:string |