| http://purl.uniprot.org/citations/3898074 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/3898074 | http://www.w3.org/2000/01/rdf-schema#comment | "In yeast alpha cells, the product encoded by the MAT alpha 1 gene of the mating-type locus is required for transcription of at least two genes, STE3 and MF alpha 1. To learn whether the lack of the MAT alpha 1 product in a and a/alpha cells is sufficient to explain the failure to express STE3 and MF alpha 1 in these cells, we have provided MAT alpha 1 product via a hybrid gene that circumvents the normal regulation of the MAT alpha 1 gene. We find by RNA blot analysis that provision of MAT alpha 1 protein permits production of STE3 and MF alpha 1 mRNA in a cells but not in a/alpha cells. These data suggest the existence of an additional regulatory mechanism that prevents expression of alpha-specific genes in a/alpha cells, even when MAT alpha 1 product is present. This regulatory mechanism appears to control expression of STE3 and MF alpha 1 at the transcriptional level rather than at the posttranscriptional level, because we show that MF alpha 1 mRNA supplied from a constitutive promoter is translated and processed in a/alpha cells to yield functional alpha-factor pheromone. This result shows further that a/alpha cells possess all the machinery necessary for pheromone maturation, even though these cells do not normally carry out these reactions."xsd:string |
| http://purl.uniprot.org/citations/3898074 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.82.17.5855"xsd:string |
| http://purl.uniprot.org/citations/3898074 | http://purl.uniprot.org/core/author | "Sprague G.F. Jr."xsd:string |
| http://purl.uniprot.org/citations/3898074 | http://purl.uniprot.org/core/author | "Bender A."xsd:string |
| http://purl.uniprot.org/citations/3898074 | http://purl.uniprot.org/core/author | "Ammerer G."xsd:string |
| http://purl.uniprot.org/citations/3898074 | http://purl.uniprot.org/core/date | "1985"xsd:gYear |
| http://purl.uniprot.org/citations/3898074 | http://purl.uniprot.org/core/name | "Proc Natl Acad Sci U S A"xsd:string |
| http://purl.uniprot.org/citations/3898074 | http://purl.uniprot.org/core/pages | "5855-5859"xsd:string |
| http://purl.uniprot.org/citations/3898074 | http://purl.uniprot.org/core/title | "Control of yeast alpha-specific genes: evidence for two blocks to expression in MATa/MAT alpha diploids."xsd:string |
| http://purl.uniprot.org/citations/3898074 | http://purl.uniprot.org/core/volume | "82"xsd:string |
| http://purl.uniprot.org/citations/3898074 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/3898074 |
| http://purl.uniprot.org/citations/3898074 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/3898074 |
| http://purl.uniprot.org/uniprot/#_P0CY06-mappedCitation-3898074 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/3898074 |
| http://purl.uniprot.org/uniprot/#_P0CY07-mappedCitation-3898074 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/3898074 |
| http://purl.uniprot.org/uniprot/#_P01149-mappedCitation-3898074 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/3898074 |
| http://purl.uniprot.org/uniprot/P0CY06 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/3898074 |
| http://purl.uniprot.org/uniprot/P0CY07 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/3898074 |
| http://purl.uniprot.org/uniprot/P01149 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/3898074 |