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http://purl.uniprot.org/citations/3941093http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/3941093http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/3941093http://www.w3.org/2000/01/rdf-schema#comment"Insulin-like growth factors I and II (IGF-I and IGF-II) were prepared from fetal calf serum and adult bovine serum by gel filtration, immunoaffinity chromatography, chromatofocusing, and reverse-phase high pressure liquid chromatography, and their complete amino acid sequences determined. IGF-I and -II are found in both adult and fetal serum. The sequence of bovine IGF-I is found to be identical to that of human IGF-I, whereas 3 out of 67 amino acid residues are found to be different between bovine and human IGF-II. The differences are located in the C-peptide region of the molecule. Bovine IGF-II shows less than 10% immunological cross-reactivity with antisera against human and rat IGF-II, but is equipotent to human IGF-II in displacing human 125I-labeled IGF-II from human placental receptor. Bovine IGF-I was equipotent to human IGF-I in both radioimmunoassays and radioreceptor assays within the limits of the assay."xsd:string
http://purl.uniprot.org/citations/3941093http://purl.org/dc/terms/identifier"doi:10.1016/s0021-9258(17)36130-6"xsd:string
http://purl.uniprot.org/citations/3941093http://purl.org/dc/terms/identifier"doi:10.1016/s0021-9258(17)36130-6"xsd:string
http://purl.uniprot.org/citations/3941093http://purl.uniprot.org/core/author"Honegger A."xsd:string
http://purl.uniprot.org/citations/3941093http://purl.uniprot.org/core/author"Honegger A."xsd:string
http://purl.uniprot.org/citations/3941093http://purl.uniprot.org/core/author"Humbel R.E."xsd:string
http://purl.uniprot.org/citations/3941093http://purl.uniprot.org/core/author"Humbel R.E."xsd:string
http://purl.uniprot.org/citations/3941093http://purl.uniprot.org/core/date"1986"xsd:gYear
http://purl.uniprot.org/citations/3941093http://purl.uniprot.org/core/date"1986"xsd:gYear
http://purl.uniprot.org/citations/3941093http://purl.uniprot.org/core/name"J. Biol. Chem."xsd:string
http://purl.uniprot.org/citations/3941093http://purl.uniprot.org/core/name"J. Biol. Chem."xsd:string
http://purl.uniprot.org/citations/3941093http://purl.uniprot.org/core/pages"569-575"xsd:string
http://purl.uniprot.org/citations/3941093http://purl.uniprot.org/core/pages"569-575"xsd:string
http://purl.uniprot.org/citations/3941093http://purl.uniprot.org/core/title"Insulin-like growth factors I and II in fetal and adult bovine serum. Purification, primary structures, and immunological cross-reactivities."xsd:string
http://purl.uniprot.org/citations/3941093http://purl.uniprot.org/core/title"Insulin-like growth factors I and II in fetal and adult bovine serum. Purification, primary structures, and immunological cross-reactivities."xsd:string
http://purl.uniprot.org/citations/3941093http://purl.uniprot.org/core/volume"261"xsd:string
http://purl.uniprot.org/citations/3941093http://purl.uniprot.org/core/volume"261"xsd:string
http://purl.uniprot.org/citations/3941093http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/3941093
http://purl.uniprot.org/citations/3941093http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/3941093
http://purl.uniprot.org/citations/3941093http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/3941093
http://purl.uniprot.org/citations/3941093http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/3941093
http://purl.uniprot.org/uniprot/P07455http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/3941093
http://purl.uniprot.org/uniprot/P07456http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/3941093