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http://purl.uniprot.org/citations/3994729http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/3994729http://www.w3.org/2000/01/rdf-schema#comment"Rat liver cytosolic thiopurine methyltransferase and microsomal thiol methyltransferase were each found to be subject to control by the absolute molar ratio of S-adenosylmethionine to S-adenosylhomocysteine using cell-free enzyme preparations. As this ratio was lowered, inhibition of both sulfhydryl xenobiotic transmethylases occurred. On the other hand, when the ratio was decreased in vivo by the administration of D,L-homocysteine thiolactone to animals, this alteration was accompanied by an inhibition of only thiopurine methyltransferase activity. Thiol methyltransferase activity was not significantly affected after drug treatment, which would suggest that there is a compartmentalization of S-adenosylhomocysteine in the intact hepatocyte."xsd:string
http://purl.uniprot.org/citations/3994729http://purl.org/dc/terms/identifier"doi:10.1016/0006-291x(85)90141-x"xsd:string
http://purl.uniprot.org/citations/3994729http://purl.uniprot.org/core/author"Smith J.T."xsd:string
http://purl.uniprot.org/citations/3994729http://purl.uniprot.org/core/author"Loo G."xsd:string
http://purl.uniprot.org/citations/3994729http://purl.uniprot.org/core/date"1985"xsd:gYear
http://purl.uniprot.org/citations/3994729http://purl.uniprot.org/core/name"Biochem Biophys Res Commun"xsd:string
http://purl.uniprot.org/citations/3994729http://purl.uniprot.org/core/pages"965-971"xsd:string
http://purl.uniprot.org/citations/3994729http://purl.uniprot.org/core/title"Effect of S-adenosylhomocysteine on sulfhydryl xenobiotic transmethylases in rat liver."xsd:string
http://purl.uniprot.org/citations/3994729http://purl.uniprot.org/core/volume"128"xsd:string
http://purl.uniprot.org/citations/3994729http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/3994729
http://purl.uniprot.org/citations/3994729http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/3994729
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http://purl.uniprot.org/uniprot/#_A0A8I5ZSG8-mappedCitation-3994729http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/3994729
http://purl.uniprot.org/uniprot/#_B0BMT6-mappedCitation-3994729http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/3994729
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http://purl.uniprot.org/uniprot/#_Q9Z0T0-mappedCitation-3994729http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/3994729
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