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http://purl.uniprot.org/citations/4000944http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/4000944http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/4000944http://www.w3.org/2000/01/rdf-schema#comment"The gene encoding muscle tropomyosin I in Drosophila is alternatively spliced in embryonic and thoracic muscle to generate two sizes classes of RNAs. By Northern blot analysis, the embryonic RNA class shows a broad RNA band of hybridization of 1.3 kb and a more sharply defined, less abundant RNA band at 1.6 kb. The thoracic class of RNAs, on the other hand, consists of a broad hybridization band at 1.7 kb and a more sharply defined band at 1.9 kb. Each size class of RNA encodes a different tropomyosin isoform. The two classes of alternatively spliced RNAs utilize the same 3' terminal exon of the gene. The DNA sequence of this exon reveals a cluster of several polyadenylation signals (AAUAAA) or polyadenylation-like signals. We show here by S1 nuclease protection analysis that at least five and possibly seven of these polyadenylation or polyadenylation-like sequences are associated with in vivo embryonic and thoracic mRNA cleavage processing sites. Six of these S1 sites are clustered within 119 bp and a seventh is located 255 bp downstream. At least one of the polyadenylation-like signal sequences appears to be an unusual AACAAA sequence. In addition we also show that these mRNAs function in vitro to synthesize muscle tropomyosins."xsd:string
http://purl.uniprot.org/citations/4000944http://purl.org/dc/terms/identifier"doi:10.1093/nar/13.5.1763"xsd:string
http://purl.uniprot.org/citations/4000944http://purl.org/dc/terms/identifier"doi:10.1093/nar/13.5.1763"xsd:string
http://purl.uniprot.org/citations/4000944http://purl.uniprot.org/core/author"Basi G.S."xsd:string
http://purl.uniprot.org/citations/4000944http://purl.uniprot.org/core/author"Basi G.S."xsd:string
http://purl.uniprot.org/citations/4000944http://purl.uniprot.org/core/author"Storti R.V."xsd:string
http://purl.uniprot.org/citations/4000944http://purl.uniprot.org/core/author"Storti R.V."xsd:string
http://purl.uniprot.org/citations/4000944http://purl.uniprot.org/core/author"Boardman M."xsd:string
http://purl.uniprot.org/citations/4000944http://purl.uniprot.org/core/author"Boardman M."xsd:string
http://purl.uniprot.org/citations/4000944http://purl.uniprot.org/core/date"1985"xsd:gYear
http://purl.uniprot.org/citations/4000944http://purl.uniprot.org/core/date"1985"xsd:gYear
http://purl.uniprot.org/citations/4000944http://purl.uniprot.org/core/name"Nucleic Acids Res."xsd:string
http://purl.uniprot.org/citations/4000944http://purl.uniprot.org/core/name"Nucleic Acids Res."xsd:string
http://purl.uniprot.org/citations/4000944http://purl.uniprot.org/core/pages"1763-1776"xsd:string
http://purl.uniprot.org/citations/4000944http://purl.uniprot.org/core/pages"1763-1776"xsd:string
http://purl.uniprot.org/citations/4000944http://purl.uniprot.org/core/title"Multiple polyadenylation sites in a Drosophila tropomyosin gene are used to generate functional mRNAs."xsd:string
http://purl.uniprot.org/citations/4000944http://purl.uniprot.org/core/title"Multiple polyadenylation sites in a Drosophila tropomyosin gene are used to generate functional mRNAs."xsd:string
http://purl.uniprot.org/citations/4000944http://purl.uniprot.org/core/volume"13"xsd:string
http://purl.uniprot.org/citations/4000944http://purl.uniprot.org/core/volume"13"xsd:string
http://purl.uniprot.org/citations/4000944http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/4000944
http://purl.uniprot.org/citations/4000944http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/4000944
http://purl.uniprot.org/citations/4000944http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/4000944
http://purl.uniprot.org/citations/4000944http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/4000944