http://purl.uniprot.org/citations/609115 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/609115 | http://www.w3.org/2000/01/rdf-schema#comment | "Mice of strain G which have Fv-4rr genotype resemble those with Fv-2rr genotype in resisting the induction of spleen foci or splenomegaly by Friend leukemia virus. However, NB-tropic Friend virus replicates well in Fv-2rr mice, but not in G mice. To determine the Fv-2 genotype, G mice were crossed with Fv-2rr mice, and the hybrids were tested for the susceptibility to NB-tropic Friend virus. The (G X Fv-2rr) F1 hybrids were similar to G. In F1 X Fv-2rr backcross generation, three types of mice appeared; 1) G type, 2) Fv-2rr type and 3) Fv-2ss type. Mice of the last type supported virus replication and developed splenomegaly. Mice of types 1), 2) and 3) appeared with the expected ratio of 2:1:1. It will be concluded that in G mice Fv-4r gene suppresses the virus replication, and hence masks the expression of Fv-2s gene. Data of F2 generation support this conclusion."xsd:string |
http://purl.uniprot.org/citations/609115 | http://purl.uniprot.org/core/author | "Ikeda H."xsd:string |
http://purl.uniprot.org/citations/609115 | http://purl.uniprot.org/core/author | "Odaka T."xsd:string |
http://purl.uniprot.org/citations/609115 | http://purl.uniprot.org/core/date | "1977"xsd:gYear |
http://purl.uniprot.org/citations/609115 | http://purl.uniprot.org/core/name | "Jpn J Exp Med"xsd:string |
http://purl.uniprot.org/citations/609115 | http://purl.uniprot.org/core/pages | "515-521"xsd:string |
http://purl.uniprot.org/citations/609115 | http://purl.uniprot.org/core/title | "Genetic resistance to Friend leukemia virus in mice: masking of Fv-2 phenotype by an epistatic gene, Fv-4."xsd:string |
http://purl.uniprot.org/citations/609115 | http://purl.uniprot.org/core/volume | "47"xsd:string |
http://purl.uniprot.org/citations/609115 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/609115 |
http://purl.uniprot.org/citations/609115 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/609115 |
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http://purl.uniprot.org/uniprot/P11370 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/609115 |
http://purl.uniprot.org/uniprot/Q62190 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/609115 |
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