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http://purl.uniprot.org/citations/6201744 | http://www.w3.org/2000/01/rdf-schema#comment | "Steroid hormones produce a response in target cells by binding to hormone-specific soluble receptors, which undergo a transformational change, leading to their interaction with chromatin and to modified gene expression. In a previous paper, we described a monoclonal antibody, BF4, that specifically recognizes and binds the non-transformed '8S' form of chicken oviduct progesterone receptor (8S-PR). We now show that BF4 does not form an immune complex with the 4S transformed form of 3H-progestin-labelled progesterone receptor, but does interact with the 8S non-transformed forms of the oestrogen, androgen and glucocorticosteroid receptors. Our results suggest that the antigenic determinant recognized by BF4 is present on a non-hormone binding unit, which we identify as a polypeptide of molecular weight (MW) 90,000 in the case of the progesterone receptor, and that this unit is common to other 8S non-transformed chicken steroid receptors."xsd:string |
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http://purl.uniprot.org/citations/6201744 | http://purl.uniprot.org/core/author | "Joab I."xsd:string |
http://purl.uniprot.org/citations/6201744 | http://purl.uniprot.org/core/author | "Binart N."xsd:string |
http://purl.uniprot.org/citations/6201744 | http://purl.uniprot.org/core/author | "Buchou T."xsd:string |
http://purl.uniprot.org/citations/6201744 | http://purl.uniprot.org/core/author | "Mester J."xsd:string |
http://purl.uniprot.org/citations/6201744 | http://purl.uniprot.org/core/author | "Baulieu E.E."xsd:string |
http://purl.uniprot.org/citations/6201744 | http://purl.uniprot.org/core/author | "Radanyi C."xsd:string |
http://purl.uniprot.org/citations/6201744 | http://purl.uniprot.org/core/author | "Catelli M.G."xsd:string |
http://purl.uniprot.org/citations/6201744 | http://purl.uniprot.org/core/author | "Renoir M."xsd:string |
http://purl.uniprot.org/citations/6201744 | http://purl.uniprot.org/core/date | "1984"xsd:gYear |
http://purl.uniprot.org/citations/6201744 | http://purl.uniprot.org/core/name | "Nature"xsd:string |
http://purl.uniprot.org/citations/6201744 | http://purl.uniprot.org/core/pages | "850-853"xsd:string |
http://purl.uniprot.org/citations/6201744 | http://purl.uniprot.org/core/title | "Common non-hormone binding component in non-transformed chick oviduct receptors of four steroid hormones."xsd:string |
http://purl.uniprot.org/citations/6201744 | http://purl.uniprot.org/core/volume | "308"xsd:string |
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