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| http://purl.uniprot.org/citations/6247002 | http://www.w3.org/2000/01/rdf-schema#comment | "The relative role of beta 1- and beta 2-adrenoceptors in mediating the stimulating effect of adrenaline on active electrogenic Na-K-transport has been assessed in experiments on rat soleus muscles in vitro and in vivo. 2 In the rat isolated soleus muscle, adrenaline (10(-6) M) increases the resting membrane potential (EM) by 5.8 mV and stimulates 22Na-efflux and ouabain-suppressible 42K-uptake by 91 and 94%, respectively. 3 All of these effects are completely blocked by propranolol (10(-5) M), whereas the beta 1-selective adrenoceptor antagonist, metoprolol, was found to be at least 50 times less potent. 4 The beta 2-adrenoceptor agonist, salbutamol, was at least 100 times as potent as H133/22 (a beta 1-selective agonist) in stimulating 22Na-efflux and 42K-influx. 5 In experiments performed under pentobarbitone anaesthesia, the intravenous injection of adrenaline (5 microgram) or salbutamol (0.5 to 50 microgram) led to a rapid and marked increase in the EM of the exposed soleus muscle. This hyperpolarizing effect could not be accounted for by the concomitant, relatively modest change in extracellular K."xsd:string |
| http://purl.uniprot.org/citations/6247002 | http://purl.org/dc/terms/identifier | "doi:10.1111/j.1476-5381.1980.tb10868.x"xsd:string |
| http://purl.uniprot.org/citations/6247002 | http://purl.uniprot.org/core/author | "Clausen T."xsd:string |
| http://purl.uniprot.org/citations/6247002 | http://purl.uniprot.org/core/author | "Flatman J.A."xsd:string |
| http://purl.uniprot.org/citations/6247002 | http://purl.uniprot.org/core/date | "1980"xsd:gYear |
| http://purl.uniprot.org/citations/6247002 | http://purl.uniprot.org/core/name | "Br J Pharmacol"xsd:string |
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| http://purl.uniprot.org/citations/6247002 | http://purl.uniprot.org/core/title | "Beta 2-adrenoceptors mediate the stimulating effect of adrenaline on active electrogenic Na-K-transport in rat soleus muscle."xsd:string |
| http://purl.uniprot.org/citations/6247002 | http://purl.uniprot.org/core/volume | "68"xsd:string |
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