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http://purl.uniprot.org/citations/6255295http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/6255295http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/6255295http://www.w3.org/2000/01/rdf-schema#comment"The hsd genes of E. coli K 12 have been cloned in phage lambda by a combination of in vitro and in vivo techniques. Three genes, whose products are required for K-specific restriction and modification, have been identified by complementation tests as hsdR, M and S. The order of these closely linked genes was established as R, M, S by analysis of the DNA of genetically characterised deletion derivatives of lambda hsd phages. The three genes are transcribed in the same direction but not necessarily as a single operon. Genetic evidence identifies two promoters, one from which transcription of hsdM and S is initiated and a second for the hsdR gene. The hsdR gene codes for a polypeptide of molecular weight approximately 130 000; hsdM for one of 62--65 000 and the hsdS gene was associated with two polypeptides of approximately 50 000. Circumstantial evidence suggest that one of these two polypeptides may be a degradation, or processed, derivative of the other. The hsdS polypeptide of E. coli B has a slightly higher mobility in an SDS-polyacrylamide gel than does that of E. coli K 12. A probe comprising most of the hsdR gene and all of the hsdM and S genes of E. coli K 12 shares extensive homology with the DNA of E. coli B but none with that of E. coli C."xsd:string
http://purl.uniprot.org/citations/6255295http://purl.org/dc/terms/identifier"doi:10.1007/bf00267350"xsd:string
http://purl.uniprot.org/citations/6255295http://purl.org/dc/terms/identifier"doi:10.1007/bf00267350"xsd:string
http://purl.uniprot.org/citations/6255295http://purl.uniprot.org/core/author"Murray N.E."xsd:string
http://purl.uniprot.org/citations/6255295http://purl.uniprot.org/core/author"Murray N.E."xsd:string
http://purl.uniprot.org/citations/6255295http://purl.uniprot.org/core/author"Sain B."xsd:string
http://purl.uniprot.org/citations/6255295http://purl.uniprot.org/core/author"Sain B."xsd:string
http://purl.uniprot.org/citations/6255295http://purl.uniprot.org/core/date"1980"xsd:gYear
http://purl.uniprot.org/citations/6255295http://purl.uniprot.org/core/date"1980"xsd:gYear
http://purl.uniprot.org/citations/6255295http://purl.uniprot.org/core/name"Mol. Gen. Genet."xsd:string
http://purl.uniprot.org/citations/6255295http://purl.uniprot.org/core/name"Mol. Gen. Genet."xsd:string
http://purl.uniprot.org/citations/6255295http://purl.uniprot.org/core/pages"35-46"xsd:string
http://purl.uniprot.org/citations/6255295http://purl.uniprot.org/core/pages"35-46"xsd:string
http://purl.uniprot.org/citations/6255295http://purl.uniprot.org/core/title"The hsd (host specificity) genes of E. coli K 12."xsd:string
http://purl.uniprot.org/citations/6255295http://purl.uniprot.org/core/title"The hsd (host specificity) genes of E. coli K 12."xsd:string
http://purl.uniprot.org/citations/6255295http://purl.uniprot.org/core/volume"180"xsd:string
http://purl.uniprot.org/citations/6255295http://purl.uniprot.org/core/volume"180"xsd:string
http://purl.uniprot.org/citations/6255295http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/6255295
http://purl.uniprot.org/citations/6255295http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/6255295
http://purl.uniprot.org/citations/6255295http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/6255295
http://purl.uniprot.org/citations/6255295http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/6255295
http://purl.uniprot.org/uniprot/P08956http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/6255295
http://purl.uniprot.org/uniprot/P05719http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/6255295