| http://purl.uniprot.org/citations/6287422 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/6287422 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/6287422 | http://www.w3.org/2000/01/rdf-schema#comment | "The rearranged lambda 2 gene of the mouse plasmacytoma cell line MOPC315 has been cloned and sequenced. A comparison of its sequence with the sequence of the unrearranged (germ-line) V, J and C gene segments shows that the sequences of the V gene segments differ at six positions. The sequence of the J and C gene segments remained unchanged. These results add support to the hypothesis that somatic mutations occur in immunoglobulin in genes and that these mutations do not involve the C gene segment. The degree of homology of the elements of the lambda 2 gene with those of the lambda 1 gene and C lambda 3 and C lambda 4 gene fragments suggest a pathway of evolution by gene duplication of the immunoglobulin lambda light chain locus. According to this scheme the original structure V0-J0C0 gave rise to a structure V0-J1C1-J11C11 by duplication of the J0C0 region. A second duplication encompassing the whole region resulted in the present structure: V1-J3C3-J1C1/V2-J2C2-J4C4."xsd:string |
| http://purl.uniprot.org/citations/6287422 | http://purl.org/dc/terms/identifier | "doi:10.1093/nar/10.13.3831"xsd:string |
| http://purl.uniprot.org/citations/6287422 | http://purl.org/dc/terms/identifier | "doi:10.1093/nar/10.13.3831"xsd:string |
| http://purl.uniprot.org/citations/6287422 | http://purl.uniprot.org/core/author | "Murialdo H."xsd:string |
| http://purl.uniprot.org/citations/6287422 | http://purl.uniprot.org/core/author | "Murialdo H."xsd:string |
| http://purl.uniprot.org/citations/6287422 | http://purl.uniprot.org/core/author | "Hozumi N."xsd:string |
| http://purl.uniprot.org/citations/6287422 | http://purl.uniprot.org/core/author | "Hozumi N."xsd:string |
| http://purl.uniprot.org/citations/6287422 | http://purl.uniprot.org/core/author | "Wu G.E."xsd:string |
| http://purl.uniprot.org/citations/6287422 | http://purl.uniprot.org/core/author | "Wu G.E."xsd:string |
| http://purl.uniprot.org/citations/6287422 | http://purl.uniprot.org/core/author | "Govindji N."xsd:string |
| http://purl.uniprot.org/citations/6287422 | http://purl.uniprot.org/core/author | "Govindji N."xsd:string |
| http://purl.uniprot.org/citations/6287422 | http://purl.uniprot.org/core/date | "1982"xsd:gYear |
| http://purl.uniprot.org/citations/6287422 | http://purl.uniprot.org/core/date | "1982"xsd:gYear |
| http://purl.uniprot.org/citations/6287422 | http://purl.uniprot.org/core/name | "Nucleic Acids Res."xsd:string |
| http://purl.uniprot.org/citations/6287422 | http://purl.uniprot.org/core/name | "Nucleic Acids Res."xsd:string |
| http://purl.uniprot.org/citations/6287422 | http://purl.uniprot.org/core/pages | "3831-3843"xsd:string |
| http://purl.uniprot.org/citations/6287422 | http://purl.uniprot.org/core/pages | "3831-3843"xsd:string |
| http://purl.uniprot.org/citations/6287422 | http://purl.uniprot.org/core/title | "Nucleotide sequence of a chromosomal rearranged lambda 2 immunoglobulin gene of mouse."xsd:string |
| http://purl.uniprot.org/citations/6287422 | http://purl.uniprot.org/core/title | "Nucleotide sequence of a chromosomal rearranged lambda 2 immunoglobulin gene of mouse."xsd:string |
| http://purl.uniprot.org/citations/6287422 | http://purl.uniprot.org/core/volume | "10"xsd:string |
| http://purl.uniprot.org/citations/6287422 | http://purl.uniprot.org/core/volume | "10"xsd:string |
| http://purl.uniprot.org/citations/6287422 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/6287422 |
| http://purl.uniprot.org/citations/6287422 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/6287422 |