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http://purl.uniprot.org/citations/6324134http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/6324134http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/6324134http://www.w3.org/2000/01/rdf-schema#comment"A full-length cDNA clone (1,894 nucleotides) of mouse cytochrome P3-450 was isolated with the Okayama-Berg vector and sequenced. An open reading frame spanned positions 61 to 1602. The first 25, and three of the last five, amino acids of P3-450 are identical to those found in the amino- and carboxy-terminus, respectively, of the rat P-450d protein. Mouse P3-450 protein has 513 residues, and a molecular weight of 58,223 with six cysteine residues. P3-450 nucleotides 305 to 352 exhibit 74% homology, and nucleotides 1068 to 1260, 69% homology, with portions of rat P-450b exons 2 and 7, respectively. P3-450 shows 62% homology in the so-called "highly conserved region" of 39 nucleotides in the rat P-450b and P-450e and the mouse P-450b. These results indicate that P3-450, P-450b and P-450e arose from a common ancestral gene. Cysteinyl peptide-coding regions were examined: P3-450 nucleotides 1405 to 1464 exhibit 61% homology, and nucleotides 502 to 552 exhibit 37% homology, when compared with their corresponding regions in the rat P-450b gene. These data support the likelihood that cysteine 456 is the thiolate ligand to the heme iron in the P3-450 enzyme active-site."xsd:string
http://purl.uniprot.org/citations/6324134http://purl.org/dc/terms/identifier"doi:10.1093/nar/12.6.2917"xsd:string
http://purl.uniprot.org/citations/6324134http://purl.org/dc/terms/identifier"doi:10.1093/nar/12.6.2917"xsd:string
http://purl.uniprot.org/citations/6324134http://purl.uniprot.org/core/author"Kimura S."xsd:string
http://purl.uniprot.org/citations/6324134http://purl.uniprot.org/core/author"Kimura S."xsd:string
http://purl.uniprot.org/citations/6324134http://purl.uniprot.org/core/author"Gonzalez F.J."xsd:string
http://purl.uniprot.org/citations/6324134http://purl.uniprot.org/core/author"Gonzalez F.J."xsd:string
http://purl.uniprot.org/citations/6324134http://purl.uniprot.org/core/author"Nebert D.W."xsd:string
http://purl.uniprot.org/citations/6324134http://purl.uniprot.org/core/author"Nebert D.W."xsd:string
http://purl.uniprot.org/citations/6324134http://purl.uniprot.org/core/date"1984"xsd:gYear
http://purl.uniprot.org/citations/6324134http://purl.uniprot.org/core/date"1984"xsd:gYear
http://purl.uniprot.org/citations/6324134http://purl.uniprot.org/core/name"Nucleic Acids Res."xsd:string
http://purl.uniprot.org/citations/6324134http://purl.uniprot.org/core/name"Nucleic Acids Res."xsd:string
http://purl.uniprot.org/citations/6324134http://purl.uniprot.org/core/pages"2917-2928"xsd:string
http://purl.uniprot.org/citations/6324134http://purl.uniprot.org/core/pages"2917-2928"xsd:string
http://purl.uniprot.org/citations/6324134http://purl.uniprot.org/core/title"Mouse cytochrome P3-450: complete cDNA and amino acid sequence."xsd:string
http://purl.uniprot.org/citations/6324134http://purl.uniprot.org/core/title"Mouse cytochrome P3-450: complete cDNA and amino acid sequence."xsd:string
http://purl.uniprot.org/citations/6324134http://purl.uniprot.org/core/volume"12"xsd:string
http://purl.uniprot.org/citations/6324134http://purl.uniprot.org/core/volume"12"xsd:string
http://purl.uniprot.org/citations/6324134http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/6324134
http://purl.uniprot.org/citations/6324134http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/6324134
http://purl.uniprot.org/citations/6324134http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/6324134
http://purl.uniprot.org/citations/6324134http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/6324134