| http://purl.uniprot.org/citations/6341993 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/6341993 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/6341993 | http://www.w3.org/2000/01/rdf-schema#comment | "Thrombospondin, a major glycoprotein released from alpha granules of thrombin-stimulated platelets, is a disulfide-bonded trimer of 160-kilodalton subunits. Cultured human foreskin and fetal lung fibroblasts secreted thrombospondin (determined by enzyme-linked immunosorbent assay) into the culture medium in a time-dependent manner (15.7 and 5.8 micrograms per 10(6) cells per 24 hr, respectively); secretion was blocked by cycloheximide. [3H]Thrombospondin was isolated from [3H]leucine-labeled fibroblast postculture medium and from cell layers with rabbit polyclonal or mouse monoclonal anti-thrombospondin coupled to staphylococcal protein A-Sepharose. The immunologically isolated [3H]thrombospondin migrated in NaDodSO4/polyacrylamide gels with purified marker platelet thrombospondin both with and without reduction. Immunofluorescence microscopy using rabbit polyclonal and mouse monoclonal anti-thrombospondin antibodies localized thrombospondin to the fibrillar extracellular matrix surrounding the cells. Thus, cultured human fibroblasts secrete thrombospondin and incorporate it into the extracellular matrix."xsd:string |
| http://purl.uniprot.org/citations/6341993 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.80.4.998"xsd:string |
| http://purl.uniprot.org/citations/6341993 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.80.4.998"xsd:string |
| http://purl.uniprot.org/citations/6341993 | http://purl.uniprot.org/core/author | "Mosher D.F."xsd:string |
| http://purl.uniprot.org/citations/6341993 | http://purl.uniprot.org/core/author | "Mosher D.F."xsd:string |
| http://purl.uniprot.org/citations/6341993 | http://purl.uniprot.org/core/author | "Jaffe E.A."xsd:string |
| http://purl.uniprot.org/citations/6341993 | http://purl.uniprot.org/core/author | "Jaffe E.A."xsd:string |
| http://purl.uniprot.org/citations/6341993 | http://purl.uniprot.org/core/author | "Leung L.K."xsd:string |
| http://purl.uniprot.org/citations/6341993 | http://purl.uniprot.org/core/author | "Leung L.K."xsd:string |
| http://purl.uniprot.org/citations/6341993 | http://purl.uniprot.org/core/author | "McKeown-Longo P.J."xsd:string |
| http://purl.uniprot.org/citations/6341993 | http://purl.uniprot.org/core/author | "McKeown-Longo P.J."xsd:string |
| http://purl.uniprot.org/citations/6341993 | http://purl.uniprot.org/core/author | "Doyle M.J."xsd:string |
| http://purl.uniprot.org/citations/6341993 | http://purl.uniprot.org/core/author | "Doyle M.J."xsd:string |
| http://purl.uniprot.org/citations/6341993 | http://purl.uniprot.org/core/author | "Ruggiero J.T."xsd:string |
| http://purl.uniprot.org/citations/6341993 | http://purl.uniprot.org/core/author | "Ruggiero J.T."xsd:string |
| http://purl.uniprot.org/citations/6341993 | http://purl.uniprot.org/core/date | "1983"xsd:gYear |
| http://purl.uniprot.org/citations/6341993 | http://purl.uniprot.org/core/date | "1983"xsd:gYear |
| http://purl.uniprot.org/citations/6341993 | http://purl.uniprot.org/core/name | "Proc. Natl. Acad. Sci. U.S.A."xsd:string |
| http://purl.uniprot.org/citations/6341993 | http://purl.uniprot.org/core/name | "Proc. Natl. Acad. Sci. U.S.A."xsd:string |
| http://purl.uniprot.org/citations/6341993 | http://purl.uniprot.org/core/pages | "998-1002"xsd:string |
| http://purl.uniprot.org/citations/6341993 | http://purl.uniprot.org/core/pages | "998-1002"xsd:string |
| http://purl.uniprot.org/citations/6341993 | http://purl.uniprot.org/core/title | "Cultured human fibroblasts synthesize and secrete thrombospondin and incorporate it into extracellular matrix."xsd:string |
| http://purl.uniprot.org/citations/6341993 | http://purl.uniprot.org/core/title | "Cultured human fibroblasts synthesize and secrete thrombospondin and incorporate it into extracellular matrix."xsd:string |