http://purl.uniprot.org/citations/6352806 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/6352806 | http://www.w3.org/2000/01/rdf-schema#comment | "A subline of the C57BL/6 mouse EL-4 thymoma produces upon stimulation with phorbol myristate acetate (PMA) a B cell growth factor (BCGF) that co-stimulates anti-IgM-stimulated splenic B cells. The BCGF present in the EL-4 thymoma culture supernatants is shown to be distinct from IL 2 by a variety of chromatographic criteria. Untreated BCGF exhibits a heterogeneity of isoelectric points (pH 6.4 to 6.6, 7.4 to 7.6, 8.5 to 8.7) all of which are more alkaline than that of IL 2 (pl 3.5 to 4.8). Neuraminidase-treated BCGF exhibits a single major pl of 9.3 that is also distinct from similarly treated IL 2. Moreover, IL 2 and BCGF exhibit distinct monomeric m.w. by SDS gel electrophoresis under nonreducing conditions (IL 2 is 21,000; BCGF is 11,000 and 15,000). The biologic activity of IL 2 is sensitive to trypsin inactivation as is BCGF activity. Thus, BCGF and IL 2 appear to be biologically and biochemically distinct glycoproteins."xsd:string |
http://purl.uniprot.org/citations/6352806 | http://purl.uniprot.org/core/author | "Paul W.E."xsd:string |
http://purl.uniprot.org/citations/6352806 | http://purl.uniprot.org/core/author | "Howard M."xsd:string |
http://purl.uniprot.org/citations/6352806 | http://purl.uniprot.org/core/author | "Farrar J.J."xsd:string |
http://purl.uniprot.org/citations/6352806 | http://purl.uniprot.org/core/author | "Fuller-Farrar J."xsd:string |
http://purl.uniprot.org/citations/6352806 | http://purl.uniprot.org/core/date | "1983"xsd:gYear |
http://purl.uniprot.org/citations/6352806 | http://purl.uniprot.org/core/name | "J Immunol"xsd:string |
http://purl.uniprot.org/citations/6352806 | http://purl.uniprot.org/core/pages | "1838-1842"xsd:string |
http://purl.uniprot.org/citations/6352806 | http://purl.uniprot.org/core/title | "Biochemical and physicochemical characterization of mouse B cell growth factor: a lymphokine distinct from interleukin 2."xsd:string |
http://purl.uniprot.org/citations/6352806 | http://purl.uniprot.org/core/volume | "131"xsd:string |
http://purl.uniprot.org/citations/6352806 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/6352806 |
http://purl.uniprot.org/citations/6352806 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/6352806 |
http://purl.uniprot.org/uniprot/#_A2AE15-mappedCitation-6352806 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/6352806 |
http://purl.uniprot.org/uniprot/#_P11680-mappedCitation-6352806 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/6352806 |
http://purl.uniprot.org/uniprot/P11680 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/6352806 |
http://purl.uniprot.org/uniprot/A2AE15 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/6352806 |