http://purl.uniprot.org/citations/6432773 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/6432773 | http://www.w3.org/2000/01/rdf-schema#comment | "GM2 containing NeuGc was a major ganglioside in the liver of mouse strains such as BALB/c, DBA/2, C3H/He, and C57BL/10, whereas WHT/Ht mouse liver did not contain GM2(NeuGc) but contained GM3(NeuGc) as a major ganglioside. Since GM3(NeuGc) is a biosynthetic precursor of GM2(NeuGc), WHT/Ht liver was considered to lack the ability to synthesize GM2(NeuGc) from GM3(NeuGc) (Hashimoto, Y., et al. (1983) J. Biochem. 93, 895-901). In this study we measured the activity of UDP-N-acetylgalactosamine : GM3(NeuGc) N-acetylgalactosaminyltransferase in the liver of BALB/c, WHT/Ht, and their progeny. The transferase activity in the microsomal fraction of BALB/c liver was 2.10 +/- 0.32 X 10(-5) units/mg protein (means +/-S.D.), whereas no activity was detected in that of WHT/Ht liver, F1 hybrids between BALB/c and WHT/Ht expressed GM2(NeuGc) as well as the enzyme activity, the level of which was almost half that in BALB/c liver 1.10 +/-0.12 X 10(-5) units/mg protein). The backcross generation of F1 to WHT/Ht segregated into two groups with respect to expression of GM2(NeuGc) and the transferase activity: 11 of the 21 mice analyzed expressed both GM2(NeuGc) and the transferase activity (1.28 +/-0.18 X 10(-5) units/mg protein), whereas the rest expressed neither. These results suggest that the expression of GM2(NeuGc) is directly regulated by the activity of UDP-N-acetylgalactosamine: GM3(NeuGc) N-acetylgalactosaminyltransferase in mouse liver."xsd:string |
http://purl.uniprot.org/citations/6432773 | http://purl.org/dc/terms/identifier | "doi:10.1093/oxfordjournals.jbchem.a134766"xsd:string |
http://purl.uniprot.org/citations/6432773 | http://purl.uniprot.org/core/author | "Hashimoto Y."xsd:string |
http://purl.uniprot.org/citations/6432773 | http://purl.uniprot.org/core/author | "Suzuki A."xsd:string |
http://purl.uniprot.org/citations/6432773 | http://purl.uniprot.org/core/author | "Abe M."xsd:string |
http://purl.uniprot.org/citations/6432773 | http://purl.uniprot.org/core/author | "Yamakawa T."xsd:string |
http://purl.uniprot.org/citations/6432773 | http://purl.uniprot.org/core/author | "Kiuchi Y."xsd:string |
http://purl.uniprot.org/citations/6432773 | http://purl.uniprot.org/core/date | "1984"xsd:gYear |
http://purl.uniprot.org/citations/6432773 | http://purl.uniprot.org/core/name | "J Biochem"xsd:string |
http://purl.uniprot.org/citations/6432773 | http://purl.uniprot.org/core/pages | "1543-1549"xsd:string |
http://purl.uniprot.org/citations/6432773 | http://purl.uniprot.org/core/title | "Genetically regulated expression of UDP-N-acetylgalactosamine: GM3(NeuGc) N-acetylgalactosaminyltransferase [EC 2.4.1.92] activity in mouse liver."xsd:string |
http://purl.uniprot.org/citations/6432773 | http://purl.uniprot.org/core/volume | "95"xsd:string |
http://purl.uniprot.org/citations/6432773 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/6432773 |
http://purl.uniprot.org/citations/6432773 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/6432773 |
http://purl.uniprot.org/uniprot/#_A0A087WRA7-mappedCitation-6432773 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/6432773 |
http://purl.uniprot.org/uniprot/#_A0A1Z4EAV4-mappedCitation-6432773 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/6432773 |
http://purl.uniprot.org/uniprot/#_A0A1W2P6F0-mappedCitation-6432773 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/6432773 |
http://purl.uniprot.org/uniprot/#_F6TGJ2-mappedCitation-6432773 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/6432773 |
http://purl.uniprot.org/uniprot/#_Q3UM45-mappedCitation-6432773 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/6432773 |
http://purl.uniprot.org/uniprot/#_Q3UN35-mappedCitation-6432773 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/6432773 |
http://purl.uniprot.org/uniprot/#_Q09200-mappedCitation-6432773 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/6432773 |
http://purl.uniprot.org/uniprot/#_Q8VDF0-mappedCitation-6432773 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/6432773 |
http://purl.uniprot.org/uniprot/#_Q9D3X1-mappedCitation-6432773 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/6432773 |
http://purl.uniprot.org/uniprot/A0A1Z4EAV4 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/6432773 |