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http://purl.uniprot.org/citations/6930639 | http://www.w3.org/2000/01/rdf-schema#comment | "Subcellular fractionation of HeLa cells was carried out under gentle conditions to isolate enzymes that cleave RNA precursors in a specific manner. Four separate activities--cleavage of HeLa cell heterogeneous nuclear RNA, the HeLa cell 45S rRNA precursor, RNA . DNA hybrids (RNase H), and the Escherichia coli tRNATyr precursor (RNase P)--were revealed by these studies. The specificity and limited nature of these cleavages suggest that they are due to eukaryotic RNA-processing enzymes. The virtual absence of random nucleases from these enzymes was demonstrated by their inability to cleave the 8000-base early mRNA precursor of bacteriophage T7, E. coli 30S rRNA precursor, or HeLa cytoplasmic poly(A)-containing RNA."xsd:string |
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http://purl.uniprot.org/citations/6930639 | http://purl.uniprot.org/core/author | "Dickson E."xsd:string |
http://purl.uniprot.org/citations/6930639 | http://purl.uniprot.org/core/author | "Yehle C.O."xsd:string |
http://purl.uniprot.org/citations/6930639 | http://purl.uniprot.org/core/date | "1980"xsd:gYear |
http://purl.uniprot.org/citations/6930639 | http://purl.uniprot.org/core/name | "Proc Natl Acad Sci U S A"xsd:string |
http://purl.uniprot.org/citations/6930639 | http://purl.uniprot.org/core/pages | "2395-2399"xsd:string |
http://purl.uniprot.org/citations/6930639 | http://purl.uniprot.org/core/title | "Specific RNA-cleaving activities from HeLa cells."xsd:string |
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