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http://purl.uniprot.org/citations/7217086 | http://www.w3.org/2000/01/rdf-schema#comment | "The prosthetic heme of cytochrome P-450 is converted during the metabolism of ethylene into an abnormal hepatic porphyrin. This porphyrin has been isolated, purified, and characterized by field desorption mass spectrometry and 360-MHz nuclear magnetic resonance spectroscopy. It has been unambiguously identified as one of the four possible isomers of N-(2-hydroxyethyl)protoporphyrin IX (isolated as the dimethyl ester). The isomer which is obtained bears the N-alkyl group on one of the two propionic acid-substituted pyrrole rings in the porphyrin. Strong support is provided by the structure of this porphyrin for our contention that the prosthetic heme of cytochrome P-450 is alkylated during attempted transfer of the catalytically-activated oxygen to the pi-bond of destructive unsaturated substrates."xsd:string |
http://purl.uniprot.org/citations/7217086 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0021-9258(19)69447-0"xsd:string |
http://purl.uniprot.org/citations/7217086 | http://purl.uniprot.org/core/author | "Ortiz de Montellano P.R."xsd:string |
http://purl.uniprot.org/citations/7217086 | http://purl.uniprot.org/core/author | "Kunze K.L."xsd:string |
http://purl.uniprot.org/citations/7217086 | http://purl.uniprot.org/core/author | "Beilan H.S."xsd:string |
http://purl.uniprot.org/citations/7217086 | http://purl.uniprot.org/core/author | "Mico B.A."xsd:string |
http://purl.uniprot.org/citations/7217086 | http://purl.uniprot.org/core/date | "1981"xsd:gYear |
http://purl.uniprot.org/citations/7217086 | http://purl.uniprot.org/core/name | "J Biol Chem"xsd:string |
http://purl.uniprot.org/citations/7217086 | http://purl.uniprot.org/core/pages | "4395-4399"xsd:string |
http://purl.uniprot.org/citations/7217086 | http://purl.uniprot.org/core/title | "Destruction of cytochrome P-450 by ethylene. Structure of the resulting prosthetic heme adduct."xsd:string |
http://purl.uniprot.org/citations/7217086 | http://purl.uniprot.org/core/volume | "256"xsd:string |
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