| http://purl.uniprot.org/citations/7499265 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/7499265 | http://www.w3.org/2000/01/rdf-schema#comment | "The ST2/T1 receptor, a homologue of the interleukin 1 receptor (IL-1R), was expressed in COS and Drosophila S2 cells as a human IgG-Fc fusion protein. While a type I IL-1RFc fusion protein bound human IL-1 in vitro, the ST2Fc fusion protein did not. Furthermore, IL-1 stimulated a synthetic interleukin-8 promoter reporter gene that was cotransfected into Jurkat cells with a full-length IL-1R type I (IL-1RI) or a chimeric receptor composed of the IL-1RI extracellular domain and ST2 intracellular domain. In contrast, IL-1 did not stimulate the interleukin-8 promoter when cotransfected with a full-length ST2 or an ST2 extracellular/IL-1R intracellular domain fusion protein. Both IL-1RI and the IL-1R/ST2R chimeric receptor also activated a receptor-associated kinase and CSBP/p38 MAP kinase. Using ST2Fc receptor, we have identified, through receptor precipitation, receptor-dot blot and surface plasmon resonance, a putative ligand of ST2 secreted from Balb/c 3T3 and human umbilical vein endothelial cells. The putative ligand was also able to stimulate CSBP/p38 MAP kinase through the ST2 receptor. These results suggest that the ST2 is not an IL-1 receptor but rather has its own cognate ligand."xsd:string |
| http://purl.uniprot.org/citations/7499265 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.270.46.27905"xsd:string |
| http://purl.uniprot.org/citations/7499265 | http://purl.uniprot.org/core/author | "Kumar S."xsd:string |
| http://purl.uniprot.org/citations/7499265 | http://purl.uniprot.org/core/author | "Young P.R."xsd:string |
| http://purl.uniprot.org/citations/7499265 | http://purl.uniprot.org/core/author | "Minnich M.D."xsd:string |
| http://purl.uniprot.org/citations/7499265 | http://purl.uniprot.org/core/date | "1995"xsd:gYear |
| http://purl.uniprot.org/citations/7499265 | http://purl.uniprot.org/core/name | "J Biol Chem"xsd:string |
| http://purl.uniprot.org/citations/7499265 | http://purl.uniprot.org/core/pages | "27905-27913"xsd:string |
| http://purl.uniprot.org/citations/7499265 | http://purl.uniprot.org/core/title | "ST2/T1 protein functionally binds to two secreted proteins from Balb/c 3T3 and human umbilical vein endothelial cells but does not bind interleukin 1."xsd:string |
| http://purl.uniprot.org/citations/7499265 | http://purl.uniprot.org/core/volume | "270"xsd:string |
| http://purl.uniprot.org/citations/7499265 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/7499265 |
| http://purl.uniprot.org/citations/7499265 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/7499265 |
| http://purl.uniprot.org/uniprot/#_G3UYU3-mappedCitation-7499265 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/7499265 |
| http://purl.uniprot.org/uniprot/#_Q32MH0-mappedCitation-7499265 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/7499265 |
| http://purl.uniprot.org/uniprot/#_Q3UM53-mappedCitation-7499265 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/7499265 |
| http://purl.uniprot.org/uniprot/#_P13504-mappedCitation-7499265 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/7499265 |
| http://purl.uniprot.org/uniprot/#_P14719-mappedCitation-7499265 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/7499265 |
| http://purl.uniprot.org/uniprot/#_Q5D095-mappedCitation-7499265 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/7499265 |
| http://purl.uniprot.org/uniprot/#_Q8C6P3-mappedCitation-7499265 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/7499265 |
| http://purl.uniprot.org/uniprot/#_Q8C833-mappedCitation-7499265 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/7499265 |
| http://purl.uniprot.org/uniprot/Q8C6P3 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/7499265 |
| http://purl.uniprot.org/uniprot/P14719 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/7499265 |
| http://purl.uniprot.org/uniprot/P13504 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/7499265 |
| http://purl.uniprot.org/uniprot/Q32MH0 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/7499265 |