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http://purl.uniprot.org/citations/7503811http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/7503811http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/7503811http://www.w3.org/2000/01/rdf-schema#comment"The search for tumour-specific markers is one of the chief goals in cancer biology. We show that the translocation t(12;16)(q13:p11) in malignant myxoid liposarcoma can be a fusion of the CHOP dominant negative transcription factor gene with a novel gene, FUS, which can result in fusion of the FUS glycine-rich protein with the whole CHOP coding region. The data support the concept that protein fusion may commonly occur in solid tumours resulting in tumour-specific markers of potential clinical importance. The data also indicate the importance of transcription disruption in the pathogenesis of solid tumours."xsd:string
http://purl.uniprot.org/citations/7503811http://purl.org/dc/terms/identifier"doi:10.1038/ng0693-175"xsd:string
http://purl.uniprot.org/citations/7503811http://purl.org/dc/terms/identifier"doi:10.1038/ng0693-175"xsd:string
http://purl.uniprot.org/citations/7503811http://purl.uniprot.org/core/author"Forster A."xsd:string
http://purl.uniprot.org/citations/7503811http://purl.uniprot.org/core/author"Forster A."xsd:string
http://purl.uniprot.org/citations/7503811http://purl.uniprot.org/core/author"Larson R."xsd:string
http://purl.uniprot.org/citations/7503811http://purl.uniprot.org/core/author"Larson R."xsd:string
http://purl.uniprot.org/citations/7503811http://purl.uniprot.org/core/author"Rabbitts T.H."xsd:string
http://purl.uniprot.org/citations/7503811http://purl.uniprot.org/core/author"Rabbitts T.H."xsd:string
http://purl.uniprot.org/citations/7503811http://purl.uniprot.org/core/author"Nathan P."xsd:string
http://purl.uniprot.org/citations/7503811http://purl.uniprot.org/core/author"Nathan P."xsd:string
http://purl.uniprot.org/citations/7503811http://purl.uniprot.org/core/date"1993"xsd:gYear
http://purl.uniprot.org/citations/7503811http://purl.uniprot.org/core/date"1993"xsd:gYear
http://purl.uniprot.org/citations/7503811http://purl.uniprot.org/core/name"Nat. Genet."xsd:string
http://purl.uniprot.org/citations/7503811http://purl.uniprot.org/core/name"Nat. Genet."xsd:string
http://purl.uniprot.org/citations/7503811http://purl.uniprot.org/core/pages"175-180"xsd:string
http://purl.uniprot.org/citations/7503811http://purl.uniprot.org/core/pages"175-180"xsd:string
http://purl.uniprot.org/citations/7503811http://purl.uniprot.org/core/title"Fusion of the dominant negative transcription regulator CHOP with a novel gene FUS by translocation t(12;16) in malignant liposarcoma."xsd:string
http://purl.uniprot.org/citations/7503811http://purl.uniprot.org/core/title"Fusion of the dominant negative transcription regulator CHOP with a novel gene FUS by translocation t(12;16) in malignant liposarcoma."xsd:string
http://purl.uniprot.org/citations/7503811http://purl.uniprot.org/core/volume"4"xsd:string
http://purl.uniprot.org/citations/7503811http://purl.uniprot.org/core/volume"4"xsd:string
http://purl.uniprot.org/citations/7503811http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/7503811
http://purl.uniprot.org/citations/7503811http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/7503811