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http://purl.uniprot.org/citations/7505206http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/7505206http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/7505206http://www.w3.org/2000/01/rdf-schema#comment"The initial adhesive interactions between circulating leukocytes and endothelia are mediated, in part, by P-selectin. We now report the expression cloning of a functional ligand for P-selectin from an HL-60 cDNA library. The predicted amino acid sequence reveals a novel mucin-like transmembrane protein. Significant binding of transfected COS cells to P-selectin requires coexpression of both the protein ligand and a fucosyltransferase. This binding is calcium dependent and can be inhibited by a neutralizing monoclonal antibody to P-selectin. Cotransfected COS cells express the ligand as a homodimer of 220 kd. A soluble ligand construct, when coexpressed with fucosyltransferase in COS cells, also mediates P-selectin binding and is immunocrossreactive with the major HL-60 glycoprotein that specifically binds P-selectin."xsd:string
http://purl.uniprot.org/citations/7505206http://purl.org/dc/terms/identifier"doi:10.1016/0092-8674(93)90327-m"xsd:string
http://purl.uniprot.org/citations/7505206http://purl.org/dc/terms/identifier"doi:10.1016/0092-8674(93)90327-m"xsd:string
http://purl.uniprot.org/citations/7505206http://purl.uniprot.org/core/author"Shaw G."xsd:string
http://purl.uniprot.org/citations/7505206http://purl.uniprot.org/core/author"Shaw G."xsd:string
http://purl.uniprot.org/citations/7505206http://purl.uniprot.org/core/author"Sako D."xsd:string
http://purl.uniprot.org/citations/7505206http://purl.uniprot.org/core/author"Sako D."xsd:string
http://purl.uniprot.org/citations/7505206http://purl.uniprot.org/core/author"Larsen G.R."xsd:string
http://purl.uniprot.org/citations/7505206http://purl.uniprot.org/core/author"Larsen G.R."xsd:string
http://purl.uniprot.org/citations/7505206http://purl.uniprot.org/core/author"Furie B."xsd:string
http://purl.uniprot.org/citations/7505206http://purl.uniprot.org/core/author"Furie B."xsd:string
http://purl.uniprot.org/citations/7505206http://purl.uniprot.org/core/author"Bean K.M."xsd:string
http://purl.uniprot.org/citations/7505206http://purl.uniprot.org/core/author"Bean K.M."xsd:string
http://purl.uniprot.org/citations/7505206http://purl.uniprot.org/core/author"Chang X.J."xsd:string
http://purl.uniprot.org/citations/7505206http://purl.uniprot.org/core/author"Chang X.J."xsd:string
http://purl.uniprot.org/citations/7505206http://purl.uniprot.org/core/author"Cumming D.A."xsd:string
http://purl.uniprot.org/citations/7505206http://purl.uniprot.org/core/author"Cumming D.A."xsd:string
http://purl.uniprot.org/citations/7505206http://purl.uniprot.org/core/author"Veldman G.M."xsd:string
http://purl.uniprot.org/citations/7505206http://purl.uniprot.org/core/author"Veldman G.M."xsd:string
http://purl.uniprot.org/citations/7505206http://purl.uniprot.org/core/author"Barone K.M."xsd:string
http://purl.uniprot.org/citations/7505206http://purl.uniprot.org/core/author"Barone K.M."xsd:string
http://purl.uniprot.org/citations/7505206http://purl.uniprot.org/core/author"Ahern T.J."xsd:string
http://purl.uniprot.org/citations/7505206http://purl.uniprot.org/core/author"Ahern T.J."xsd:string