| http://purl.uniprot.org/citations/7533327 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/7533327 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/7533327 | http://www.w3.org/2000/01/rdf-schema#comment | "CD40 is a receptor on the surface of B lymphocytes, the activation of which leads to B cell survival, growth, and differentiation. A yeast two-hybrid screen identified a gene, CRAF1, encoding a protein that interacts directly with the CD40 cytoplasmic tail through a region of similarity to the tumor necrosis factor-alpha (TNF-alpha) receptor-associated factors. Overexpression of a truncated CRAF1 gene inhibited CD40-mediated up-regulation of CD23. A region of CRAF1 was similar to the TNF-alpha receptor-associated factors TRAF1 and TRAF2 and so defined a shared TRAF-C domain that was necessary and sufficient for CD40 binding and homodimerization. The CRAF1 sequence also predicted a long amphipathic helix, a pattern of five zinc fingers, and a zinc ring finger. It is likely that other members of the TNF receptor superfamily use CRAF-related proteins in their signal transduction processes."xsd:string |
| http://purl.uniprot.org/citations/7533327 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.7533327"xsd:string |
| http://purl.uniprot.org/citations/7533327 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.7533327"xsd:string |
| http://purl.uniprot.org/citations/7533327 | http://purl.uniprot.org/core/author | "Baltimore D."xsd:string |
| http://purl.uniprot.org/citations/7533327 | http://purl.uniprot.org/core/author | "Baltimore D."xsd:string |
| http://purl.uniprot.org/citations/7533327 | http://purl.uniprot.org/core/author | "Cheng G."xsd:string |
| http://purl.uniprot.org/citations/7533327 | http://purl.uniprot.org/core/author | "Cheng G."xsd:string |
| http://purl.uniprot.org/citations/7533327 | http://purl.uniprot.org/core/author | "Cleary A.M."xsd:string |
| http://purl.uniprot.org/citations/7533327 | http://purl.uniprot.org/core/author | "Cleary A.M."xsd:string |
| http://purl.uniprot.org/citations/7533327 | http://purl.uniprot.org/core/author | "Lederman S."xsd:string |
| http://purl.uniprot.org/citations/7533327 | http://purl.uniprot.org/core/author | "Lederman S."xsd:string |
| http://purl.uniprot.org/citations/7533327 | http://purl.uniprot.org/core/author | "Hong D.I."xsd:string |
| http://purl.uniprot.org/citations/7533327 | http://purl.uniprot.org/core/author | "Hong D.I."xsd:string |
| http://purl.uniprot.org/citations/7533327 | http://purl.uniprot.org/core/author | "Ye Z.S."xsd:string |
| http://purl.uniprot.org/citations/7533327 | http://purl.uniprot.org/core/author | "Ye Z.S."xsd:string |
| http://purl.uniprot.org/citations/7533327 | http://purl.uniprot.org/core/date | "1995"xsd:gYear |
| http://purl.uniprot.org/citations/7533327 | http://purl.uniprot.org/core/date | "1995"xsd:gYear |
| http://purl.uniprot.org/citations/7533327 | http://purl.uniprot.org/core/name | "Science"xsd:string |
| http://purl.uniprot.org/citations/7533327 | http://purl.uniprot.org/core/name | "Science"xsd:string |
| http://purl.uniprot.org/citations/7533327 | http://purl.uniprot.org/core/pages | "1494-1498"xsd:string |
| http://purl.uniprot.org/citations/7533327 | http://purl.uniprot.org/core/pages | "1494-1498"xsd:string |
| http://purl.uniprot.org/citations/7533327 | http://purl.uniprot.org/core/title | "Involvement of CRAF1, a relative of TRAF, in CD40 signaling."xsd:string |
| http://purl.uniprot.org/citations/7533327 | http://purl.uniprot.org/core/title | "Involvement of CRAF1, a relative of TRAF, in CD40 signaling."xsd:string |