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| http://purl.uniprot.org/citations/7535475 | http://www.w3.org/2000/01/rdf-schema#comment | "The interleukin-1 beta (IL-1 beta) converting enzyme (ICE) processes the inactive IL-1 beta precursor to the proinflammatory cytokine. Adherent monocytes from mice harboring a disrupted ICE gene (ICE-/-) did not export IL-1 beta or interleukin-1 alpha (IL-1 alpha) after stimulation with lipopolysaccharide. Export of tumor necrosis factor-alpha and interleukin-6 (IL-6) from these cells was also diminished. Thymocytes from ICE-/-mice were sensitive to apoptosis induced by dexamethasone or ionizing radiation, but were resistant to apoptosis induced by Fas antibody. Despite this defect in apoptosis, ICE-/- mice proceed normally through development."xsd:string |
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| http://purl.uniprot.org/citations/7535475 | http://purl.uniprot.org/core/author | "Flavell R.A."xsd:string |
| http://purl.uniprot.org/citations/7535475 | http://purl.uniprot.org/core/author | "Livingston D.J."xsd:string |
| http://purl.uniprot.org/citations/7535475 | http://purl.uniprot.org/core/author | "Lippke J.A."xsd:string |
| http://purl.uniprot.org/citations/7535475 | http://purl.uniprot.org/core/author | "Harding M.W."xsd:string |
| http://purl.uniprot.org/citations/7535475 | http://purl.uniprot.org/core/author | "Kuida K."xsd:string |
| http://purl.uniprot.org/citations/7535475 | http://purl.uniprot.org/core/author | "Su M.S."xsd:string |
| http://purl.uniprot.org/citations/7535475 | http://purl.uniprot.org/core/author | "Ku G."xsd:string |
| http://purl.uniprot.org/citations/7535475 | http://purl.uniprot.org/core/date | "1995"xsd:gYear |
| http://purl.uniprot.org/citations/7535475 | http://purl.uniprot.org/core/name | "Science"xsd:string |
| http://purl.uniprot.org/citations/7535475 | http://purl.uniprot.org/core/pages | "2000-2003"xsd:string |
| http://purl.uniprot.org/citations/7535475 | http://purl.uniprot.org/core/title | "Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme."xsd:string |
| http://purl.uniprot.org/citations/7535475 | http://purl.uniprot.org/core/volume | "267"xsd:string |
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