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http://purl.uniprot.org/citations/7536343http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/7536343http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/7536343http://www.w3.org/2000/01/rdf-schema#comment"Fas is a cell surface receptor that controls a poorly understood signal transduction pathway that leads to cell death by means of apoptosis. A protein tyrosine phosphatase, FAP-1, capable of interacting with the cytosolic domain of Fas, was identified. The carboxyl terminal 15 amino acids of Fas are necessary and sufficient for interaction with FAP-1. FAP-1 expression is highest in tissues and cell lines that are relatively resistant to Fas-mediated cytotoxicity. Gene transfer-mediated elevations in FAP-1 partially abolished Fas-induced apoptosis in a T cell line. These findings are consistent with an inhibitory effect of FAP-1 on Fas signal transduction."xsd:string
http://purl.uniprot.org/citations/7536343http://purl.org/dc/terms/identifier"doi:10.1126/science.7536343"xsd:string
http://purl.uniprot.org/citations/7536343http://purl.org/dc/terms/identifier"doi:10.1126/science.7536343"xsd:string
http://purl.uniprot.org/citations/7536343http://purl.uniprot.org/core/author"Irie S."xsd:string
http://purl.uniprot.org/citations/7536343http://purl.uniprot.org/core/author"Irie S."xsd:string
http://purl.uniprot.org/citations/7536343http://purl.uniprot.org/core/author"Sato T."xsd:string
http://purl.uniprot.org/citations/7536343http://purl.uniprot.org/core/author"Sato T."xsd:string
http://purl.uniprot.org/citations/7536343http://purl.uniprot.org/core/author"Reed J.C."xsd:string
http://purl.uniprot.org/citations/7536343http://purl.uniprot.org/core/author"Reed J.C."xsd:string
http://purl.uniprot.org/citations/7536343http://purl.uniprot.org/core/author"Kitada S."xsd:string
http://purl.uniprot.org/citations/7536343http://purl.uniprot.org/core/author"Kitada S."xsd:string
http://purl.uniprot.org/citations/7536343http://purl.uniprot.org/core/date"1995"xsd:gYear
http://purl.uniprot.org/citations/7536343http://purl.uniprot.org/core/date"1995"xsd:gYear
http://purl.uniprot.org/citations/7536343http://purl.uniprot.org/core/name"Science"xsd:string
http://purl.uniprot.org/citations/7536343http://purl.uniprot.org/core/name"Science"xsd:string
http://purl.uniprot.org/citations/7536343http://purl.uniprot.org/core/pages"411-415"xsd:string
http://purl.uniprot.org/citations/7536343http://purl.uniprot.org/core/pages"411-415"xsd:string
http://purl.uniprot.org/citations/7536343http://purl.uniprot.org/core/title"FAP-1: a protein tyrosine phosphatase that associates with Fas."xsd:string
http://purl.uniprot.org/citations/7536343http://purl.uniprot.org/core/title"FAP-1: a protein tyrosine phosphatase that associates with Fas."xsd:string
http://purl.uniprot.org/citations/7536343http://purl.uniprot.org/core/volume"268"xsd:string
http://purl.uniprot.org/citations/7536343http://purl.uniprot.org/core/volume"268"xsd:string
http://purl.uniprot.org/citations/7536343http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/7536343
http://purl.uniprot.org/citations/7536343http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/7536343