| http://purl.uniprot.org/citations/7539918 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/7539918 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/7539918 | http://www.w3.org/2000/01/rdf-schema#comment | "Hypoxia-inducible factor 1 (HIF-1) is found in mammalian cells cultured under reduced O2 tension and is necessary for transcriptional activation mediated by the erythropoietin gene enhancer in hypoxic cells. We show that both HIF-1 subunits are basic-helix-loop-helix proteins containing a PAS domain, defined by its presence in the Drosophila Per and Sim proteins and in the mammalian ARNT and AHR proteins. HIF-1 alpha is most closely related to Sim. HIF-1 beta is a series of ARNT gene products, which can thus heterodimerize with either HIF-1 alpha or AHR. HIF-1 alpha and HIF-1 beta (ARNT) RNA and protein levels were induced in cells exposed to 1% O2 and decayed rapidly upon return of the cells to 20% O2, consistent with the role of HIF-1 as a mediator of transcriptional responses to hypoxia."xsd:string |
| http://purl.uniprot.org/citations/7539918 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.92.12.5510"xsd:string |
| http://purl.uniprot.org/citations/7539918 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.92.12.5510"xsd:string |
| http://purl.uniprot.org/citations/7539918 | http://purl.uniprot.org/core/author | "Wang G.L."xsd:string |
| http://purl.uniprot.org/citations/7539918 | http://purl.uniprot.org/core/author | "Wang G.L."xsd:string |
| http://purl.uniprot.org/citations/7539918 | http://purl.uniprot.org/core/author | "Jiang B.-H."xsd:string |
| http://purl.uniprot.org/citations/7539918 | http://purl.uniprot.org/core/author | "Jiang B.-H."xsd:string |
| http://purl.uniprot.org/citations/7539918 | http://purl.uniprot.org/core/author | "Rue E.A."xsd:string |
| http://purl.uniprot.org/citations/7539918 | http://purl.uniprot.org/core/author | "Rue E.A."xsd:string |
| http://purl.uniprot.org/citations/7539918 | http://purl.uniprot.org/core/author | "Semenza G.L."xsd:string |
| http://purl.uniprot.org/citations/7539918 | http://purl.uniprot.org/core/author | "Semenza G.L."xsd:string |
| http://purl.uniprot.org/citations/7539918 | http://purl.uniprot.org/core/date | "1995"xsd:gYear |
| http://purl.uniprot.org/citations/7539918 | http://purl.uniprot.org/core/date | "1995"xsd:gYear |
| http://purl.uniprot.org/citations/7539918 | http://purl.uniprot.org/core/name | "Proc. Natl. Acad. Sci. U.S.A."xsd:string |
| http://purl.uniprot.org/citations/7539918 | http://purl.uniprot.org/core/name | "Proc. Natl. Acad. Sci. U.S.A."xsd:string |
| http://purl.uniprot.org/citations/7539918 | http://purl.uniprot.org/core/pages | "5510-5514"xsd:string |
| http://purl.uniprot.org/citations/7539918 | http://purl.uniprot.org/core/pages | "5510-5514"xsd:string |
| http://purl.uniprot.org/citations/7539918 | http://purl.uniprot.org/core/title | "Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension."xsd:string |
| http://purl.uniprot.org/citations/7539918 | http://purl.uniprot.org/core/title | "Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension."xsd:string |
| http://purl.uniprot.org/citations/7539918 | http://purl.uniprot.org/core/volume | "92"xsd:string |
| http://purl.uniprot.org/citations/7539918 | http://purl.uniprot.org/core/volume | "92"xsd:string |
| http://purl.uniprot.org/citations/7539918 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/7539918 |
| http://purl.uniprot.org/citations/7539918 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/7539918 |