| http://purl.uniprot.org/citations/7544442 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/7544442 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/7544442 | http://www.w3.org/2000/01/rdf-schema#comment | "The male-specific transplantation antigen, H-Y, causes rejection of male tissue grafts by genotypically identical female mice and contributes to the rejection of human leukocyte antigen-matched male organ grafts by human females. Although first recognized 40 years ago, the identity of H-Y has remained elusive. T cells detect several distinct H-Y epitopes, and these are probably peptides, derived from intracellular proteins, that are presented at the cell surface with major histocompatibility complex (MHC) molecules. In the mouse, the gene(s) controlling H-Y expression (Hya) are located on the short arm of the Y chromosome between the zinc-finger genes Zfy-1 and Zfy-2. We have recently identified Smcy, a ubiquitously expressed gene, in this region and its X-chromosome homologue, Smcx. Here we report that Smcy encodes an H-YKk epitope that is defined by the octamer peptide TENSGKDI: no similar peptide is found in Smcx. These findings provide a genetic basis for the antigenic difference between males and females that contributes towards a tissue transplant rejection response."xsd:string |
| http://purl.uniprot.org/citations/7544442 | http://purl.org/dc/terms/identifier | "doi:10.1038/376695a0"xsd:string |
| http://purl.uniprot.org/citations/7544442 | http://purl.org/dc/terms/identifier | "doi:10.1038/376695a0"xsd:string |
| http://purl.uniprot.org/citations/7544442 | http://purl.uniprot.org/core/author | "Scott D.M."xsd:string |
| http://purl.uniprot.org/citations/7544442 | http://purl.uniprot.org/core/author | "Scott D.M."xsd:string |
| http://purl.uniprot.org/citations/7544442 | http://purl.uniprot.org/core/author | "Ehrmann I.E."xsd:string |
| http://purl.uniprot.org/citations/7544442 | http://purl.uniprot.org/core/author | "Ehrmann I.E."xsd:string |
| http://purl.uniprot.org/citations/7544442 | http://purl.uniprot.org/core/author | "Simpson E."xsd:string |
| http://purl.uniprot.org/citations/7544442 | http://purl.uniprot.org/core/author | "Simpson E."xsd:string |
| http://purl.uniprot.org/citations/7544442 | http://purl.uniprot.org/core/author | "Mitchell M.J."xsd:string |
| http://purl.uniprot.org/citations/7544442 | http://purl.uniprot.org/core/author | "Mitchell M.J."xsd:string |
| http://purl.uniprot.org/citations/7544442 | http://purl.uniprot.org/core/author | "Agulnik A.I."xsd:string |
| http://purl.uniprot.org/citations/7544442 | http://purl.uniprot.org/core/author | "Agulnik A.I."xsd:string |
| http://purl.uniprot.org/citations/7544442 | http://purl.uniprot.org/core/author | "Bishop C.E."xsd:string |
| http://purl.uniprot.org/citations/7544442 | http://purl.uniprot.org/core/author | "Bishop C.E."xsd:string |
| http://purl.uniprot.org/citations/7544442 | http://purl.uniprot.org/core/author | "Ellis P.S."xsd:string |
| http://purl.uniprot.org/citations/7544442 | http://purl.uniprot.org/core/author | "Ellis P.S."xsd:string |
| http://purl.uniprot.org/citations/7544442 | http://purl.uniprot.org/core/date | "1995"xsd:gYear |
| http://purl.uniprot.org/citations/7544442 | http://purl.uniprot.org/core/date | "1995"xsd:gYear |
| http://purl.uniprot.org/citations/7544442 | http://purl.uniprot.org/core/name | "Nature"xsd:string |
| http://purl.uniprot.org/citations/7544442 | http://purl.uniprot.org/core/name | "Nature"xsd:string |
| http://purl.uniprot.org/citations/7544442 | http://purl.uniprot.org/core/pages | "695-698"xsd:string |
| http://purl.uniprot.org/citations/7544442 | http://purl.uniprot.org/core/pages | "695-698"xsd:string |