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http://purl.uniprot.org/citations/7557362 | http://www.w3.org/2000/01/rdf-schema#comment | "To identify genes important in fat-cell metabolism and development, we have screened Drosophila stocks carrying an engineered transposable element that can reveal the presence of nearby enhancer elements. We have identified those "enhancer-trap lines" that contain transposable P elements integrated near fat-cell specific enhancer elements. We anticipate that the genes associated with these enhancers will provide information concerning fat-cell function and serve as target genes for studying fat-cell specific gene expression. Furthermore, the identification of enhancer-trap lines active in the developing fat cell should provide an entry point into the molecular and genetic analysis of early fat-cell development. Analysis of two lines has revealed that the transcription factors svp, a steroid-hormone receptor, and Kr, a zinc-finger protein, are present in the fat body; these factors are likely to be involved in fat-cell gene expression. In two other lines, beta-galactosidase was detected in a subset of adepithelial cells that may be the precursors to the adult fat cell. And finally, in a single line transgene activity is present in the progenitor cells of the embryonic fat body. The genes associated with these enhancer-trap lines may be involved in fat-cell development."xsd:string |
http://purl.uniprot.org/citations/7557362 | http://purl.org/dc/terms/identifier | "doi:10.1139/g95-065"xsd:string |
http://purl.uniprot.org/citations/7557362 | http://purl.uniprot.org/core/author | "Ghosh M."xsd:string |
http://purl.uniprot.org/citations/7557362 | http://purl.uniprot.org/core/author | "Johnson W."xsd:string |
http://purl.uniprot.org/citations/7557362 | http://purl.uniprot.org/core/author | "Hoshizaki D.K."xsd:string |
http://purl.uniprot.org/citations/7557362 | http://purl.uniprot.org/core/author | "Lunz R."xsd:string |
http://purl.uniprot.org/citations/7557362 | http://purl.uniprot.org/core/date | "1995"xsd:gYear |
http://purl.uniprot.org/citations/7557362 | http://purl.uniprot.org/core/name | "Genome"xsd:string |
http://purl.uniprot.org/citations/7557362 | http://purl.uniprot.org/core/pages | "497-506"xsd:string |
http://purl.uniprot.org/citations/7557362 | http://purl.uniprot.org/core/title | "Identification of fat-cell enhancer activity in Drosophila melanogaster using P-element enhancer traps."xsd:string |
http://purl.uniprot.org/citations/7557362 | http://purl.uniprot.org/core/volume | "38"xsd:string |
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