http://purl.uniprot.org/citations/7558941 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/7558941 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/7558941 | http://www.w3.org/2000/01/rdf-schema#comment | "The HLA-G nonclassic MHC class I gene expressed at the maternal-fetal interface may be involved in cell protection against NK cell lysis. HLA-G mRNA is observed in different adult or fetal human cells and exhibits four alternative forms: HLA-G1, HLA-G2, HLA-G3, and HLA-G4 lacking, respectively, exon 7; exons 7 and 3, exons 7, 3, and 4; exons 7 and 4. Because exon 5 encodes the transmembrane domain of the HLA-G antigen, none of these transcripts could give a soluble form as detected in supernatant of trophoblasts. In this report, we describe an additional alternatively spliced for of HLA-G transcript (HLA-G5) present in adult PBMCs and first-trimester trophoblasts that contains intron 4. Moreover, as with all other transcripts, HLA-G5, is devoid of exon 7. Its relative frequency is, respectively, approximately 1:8 and approximately 1:26 in adult PBMCs and first-trimester trophoblasts. The presence of intron 4 generates a stop codon that excludes transmembrane region (exon 5) of the HLA-G molecule and therefore might produce a soluble antigen. These results are discussed with regard to data on soluble forms of classic HLA antigens and the possible role of HLA-G."xsd:string |
http://purl.uniprot.org/citations/7558941 | http://purl.org/dc/terms/identifier | "doi:10.1016/0198-8859(95)00009-s"xsd:string |
http://purl.uniprot.org/citations/7558941 | http://purl.org/dc/terms/identifier | "doi:10.1016/0198-8859(95)00009-s"xsd:string |
http://purl.uniprot.org/citations/7558941 | http://purl.uniprot.org/core/author | "Moreau P."xsd:string |
http://purl.uniprot.org/citations/7558941 | http://purl.uniprot.org/core/author | "Moreau P."xsd:string |
http://purl.uniprot.org/citations/7558941 | http://purl.uniprot.org/core/author | "Kirszenbaum M."xsd:string |
http://purl.uniprot.org/citations/7558941 | http://purl.uniprot.org/core/author | "Kirszenbaum M."xsd:string |
http://purl.uniprot.org/citations/7558941 | http://purl.uniprot.org/core/author | "Prost S."xsd:string |
http://purl.uniprot.org/citations/7558941 | http://purl.uniprot.org/core/author | "Prost S."xsd:string |
http://purl.uniprot.org/citations/7558941 | http://purl.uniprot.org/core/author | "Dausset J."xsd:string |
http://purl.uniprot.org/citations/7558941 | http://purl.uniprot.org/core/author | "Dausset J."xsd:string |
http://purl.uniprot.org/citations/7558941 | http://purl.uniprot.org/core/author | "Carosella E."xsd:string |
http://purl.uniprot.org/citations/7558941 | http://purl.uniprot.org/core/author | "Carosella E."xsd:string |
http://purl.uniprot.org/citations/7558941 | http://purl.uniprot.org/core/author | "Gluckman E."xsd:string |
http://purl.uniprot.org/citations/7558941 | http://purl.uniprot.org/core/author | "Gluckman E."xsd:string |
http://purl.uniprot.org/citations/7558941 | http://purl.uniprot.org/core/author | "Teyssier M."xsd:string |
http://purl.uniprot.org/citations/7558941 | http://purl.uniprot.org/core/author | "Teyssier M."xsd:string |
http://purl.uniprot.org/citations/7558941 | http://purl.uniprot.org/core/date | "1995"xsd:gYear |
http://purl.uniprot.org/citations/7558941 | http://purl.uniprot.org/core/date | "1995"xsd:gYear |
http://purl.uniprot.org/citations/7558941 | http://purl.uniprot.org/core/name | "Hum. Immunol."xsd:string |
http://purl.uniprot.org/citations/7558941 | http://purl.uniprot.org/core/name | "Hum. Immunol."xsd:string |
http://purl.uniprot.org/citations/7558941 | http://purl.uniprot.org/core/pages | "231-236"xsd:string |
http://purl.uniprot.org/citations/7558941 | http://purl.uniprot.org/core/pages | "231-236"xsd:string |