| http://purl.uniprot.org/citations/7567982 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/7567982 | http://www.w3.org/2000/01/rdf-schema#comment | "Tsk/Itk and Btk are members of the pleckstrin-homology (PH) domain-containing tyrosine kinase family. The PH domain has been demonstrated to be able to interact with beta gamma subunits of heterotrimeric guanine nucleotide-binding proteins (G proteins) (G beta gamma) and phospholipids. Using cotransfection assays, we show here that the kinase activities of Tsk and Btk are stimulated by certain G beta gamma subunits. Furthermore, using an in vitro reconstitution assay with purified bovine brain G beta gamma subunits and the immunoprecipitated Tsk, we find that Tsk kinase activity is increased by G beta gamma subunits and another membrane factor(s). These results indicate that this family of tyrosine kinases could be an effector of heterotrimeric G proteins."xsd:string |
| http://purl.uniprot.org/citations/7567982 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.92.19.8601"xsd:string |
| http://purl.uniprot.org/citations/7567982 | http://purl.uniprot.org/core/author | "Wan Y."xsd:string |
| http://purl.uniprot.org/citations/7567982 | http://purl.uniprot.org/core/author | "Huang X.Y."xsd:string |
| http://purl.uniprot.org/citations/7567982 | http://purl.uniprot.org/core/author | "Langhans-Rajasekaran S.A."xsd:string |
| http://purl.uniprot.org/citations/7567982 | http://purl.uniprot.org/core/date | "1995"xsd:gYear |
| http://purl.uniprot.org/citations/7567982 | http://purl.uniprot.org/core/name | "Proc Natl Acad Sci U S A"xsd:string |
| http://purl.uniprot.org/citations/7567982 | http://purl.uniprot.org/core/pages | "8601-8605"xsd:string |
| http://purl.uniprot.org/citations/7567982 | http://purl.uniprot.org/core/title | "Activation of Tsk and Btk tyrosine kinases by G protein beta gamma subunits."xsd:string |
| http://purl.uniprot.org/citations/7567982 | http://purl.uniprot.org/core/volume | "92"xsd:string |
| http://purl.uniprot.org/citations/7567982 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/7567982 |
| http://purl.uniprot.org/citations/7567982 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/7567982 |
| http://purl.uniprot.org/uniprot/#_O14775-mappedCitation-7567982 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/7567982 |
| http://purl.uniprot.org/uniprot/#_P16520-mappedCitation-7567982 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/7567982 |
| http://purl.uniprot.org/uniprot/#_Q06187-mappedCitation-7567982 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/7567982 |
| http://purl.uniprot.org/uniprot/#_P50150-mappedCitation-7567982 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/7567982 |
| http://purl.uniprot.org/uniprot/#_P50151-mappedCitation-7567982 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/7567982 |
| http://purl.uniprot.org/uniprot/#_O14610-mappedCitation-7567982 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/7567982 |
| http://purl.uniprot.org/uniprot/#_O60262-mappedCitation-7567982 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/7567982 |
| http://purl.uniprot.org/uniprot/#_P59768-mappedCitation-7567982 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/7567982 |
| http://purl.uniprot.org/uniprot/#_P62873-mappedCitation-7567982 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/7567982 |
| http://purl.uniprot.org/uniprot/#_P62879-mappedCitation-7567982 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/7567982 |
| http://purl.uniprot.org/uniprot/#_P61952-mappedCitation-7567982 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/7567982 |
| http://purl.uniprot.org/uniprot/#_P63211-mappedCitation-7567982 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/7567982 |