| http://purl.uniprot.org/citations/7569953 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/7569953 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/7569953 | http://www.w3.org/2000/01/rdf-schema#comment | "Cdc2 is the cyclin-dependent kinase that controls entry of cells into mitosis. Phosphorylation of Cdc2 on threonine-14 and tyrosine-15 inhibits the activity of the enzyme and prevents premature initiation of mitosis. Although Wee1 has been identified as the kinase that phosphorylates tyrosine-15 in various organisms, the threonine-14-specific kinase has not been isolated. A complementary DNA was cloned from Xenopus that encodes Myt1, a member of the Wee1 family that was discovered to phosphorylate Cdc2 efficiently on both threonine-14 and tyrosine-15. Myt1 is a membrane-associated protein that contains a putative transmembrane segment. Immunodepletion studies suggested that Myt1 is the predominant threonine-14-specific kinase in Xenopus egg extracts. Myt1 activity is highly regulated during the cell cycle, suggesting that this relative of Wee1 plays a role in mitotic control."xsd:string |
| http://purl.uniprot.org/citations/7569953 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.270.5233.86"xsd:string |
| http://purl.uniprot.org/citations/7569953 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.270.5233.86"xsd:string |
| http://purl.uniprot.org/citations/7569953 | http://purl.uniprot.org/core/author | "Dunphy W.G."xsd:string |
| http://purl.uniprot.org/citations/7569953 | http://purl.uniprot.org/core/author | "Dunphy W.G."xsd:string |
| http://purl.uniprot.org/citations/7569953 | http://purl.uniprot.org/core/author | "Kumagai A."xsd:string |
| http://purl.uniprot.org/citations/7569953 | http://purl.uniprot.org/core/author | "Kumagai A."xsd:string |
| http://purl.uniprot.org/citations/7569953 | http://purl.uniprot.org/core/author | "Mueller P.R."xsd:string |
| http://purl.uniprot.org/citations/7569953 | http://purl.uniprot.org/core/author | "Mueller P.R."xsd:string |
| http://purl.uniprot.org/citations/7569953 | http://purl.uniprot.org/core/author | "Coleman T.R."xsd:string |
| http://purl.uniprot.org/citations/7569953 | http://purl.uniprot.org/core/author | "Coleman T.R."xsd:string |
| http://purl.uniprot.org/citations/7569953 | http://purl.uniprot.org/core/date | "1995"xsd:gYear |
| http://purl.uniprot.org/citations/7569953 | http://purl.uniprot.org/core/date | "1995"xsd:gYear |
| http://purl.uniprot.org/citations/7569953 | http://purl.uniprot.org/core/name | "Science"xsd:string |
| http://purl.uniprot.org/citations/7569953 | http://purl.uniprot.org/core/name | "Science"xsd:string |
| http://purl.uniprot.org/citations/7569953 | http://purl.uniprot.org/core/pages | "86-90"xsd:string |
| http://purl.uniprot.org/citations/7569953 | http://purl.uniprot.org/core/pages | "86-90"xsd:string |
| http://purl.uniprot.org/citations/7569953 | http://purl.uniprot.org/core/title | "Myt1: a membrane-associated inhibitory kinase that phosphorylates Cdc2 on both threonine-14 and tyrosine-15."xsd:string |
| http://purl.uniprot.org/citations/7569953 | http://purl.uniprot.org/core/title | "Myt1: a membrane-associated inhibitory kinase that phosphorylates Cdc2 on both threonine-14 and tyrosine-15."xsd:string |
| http://purl.uniprot.org/citations/7569953 | http://purl.uniprot.org/core/volume | "270"xsd:string |
| http://purl.uniprot.org/citations/7569953 | http://purl.uniprot.org/core/volume | "270"xsd:string |
| http://purl.uniprot.org/citations/7569953 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/7569953 |
| http://purl.uniprot.org/citations/7569953 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/7569953 |